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PAPERS PUBLISHED IN 1999

This list is arranged by the name of the first author. Any omissions, mistakes and inconsistencies please communicate to the authors of compilation (michal@5z.com). (If you are pointing to any reference, please use its ID# -- the last number in the reference.) You are welcome to use this compilation in your work. Proper way to quote it in your paper is: Lebl M., Leblova Z.: Dynamic database of references in molecular diversity. Internet http://www.5z.com.


Recently added entries are marked in bold

  1. Anonymous. (1999) BASF plans to accelerate catalyst research. Performance Chemicals International, 14, 7-7. #14716

  2. Anonymous. (1999) Combinatorial chemistry for molecular sieves. Advanced Materials, 11, 1330. #14905

  3. Anonymous. (1999) Latest developments in combinatorial chemistry, discovery to process development. Chim. Oggi, 17, 30-31. #12912

  4. Abate, P., Conroy, J.L., & Seto, C.T. (1999) Combinatorial library of serine and cysteine protease inhibitors that interact with both the S and S' binding sites. J. Med. Chem., 42, 4001-4009. #13895

  5. Abato, P., Conroy, J.L., & Seto, C.T. (1999) Combinatorial library of serine and cysteine protease inhibitors that interact with both the S and S' binding sites. J. Med. Chem., 42, 4001-4009. #15612

  6. Abele, R., & Tampe, R. (1999) Function of the transport complex TAP in cellular immune recognition. Biochimica et Biophysica Acta - Biomembranes, 1461, 405-419. #13896

  7. Adams, J.H., Cook, R.M., Hudson, D., Jammalamadaka, V., Lyttle, M.H. & Songster, M.F. (1999) Improved supports and methods for solid phase mediated transformations. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries. (pp. 23-30). Mayflower Scientific Limited, Birmingham. #13454

  8. Adang, A.E.P., Peters, C.A.M., Gerritsma, S., De Zwart, E., & Veeneman, G. (1999) Solution-phase and solid-phase synthesis of novel transition state inhibitors of coagulation enzymes incorporating a piperidinyl moiety. Bioorg. Med. Chem. Lett., 9, 1227-1232. #12857

  9. Adda, C.G., Tilley, L., Anders, R.F., & Foley, M. (1999) Isolation of peptides that mimic epitopes on a malarial antigen from random peptide libraries displayed on phage. Infec. Immunity, 67, 4679-4688. #13468

  10. Adermann, K., Wattler, F., Wattler, S., Heine, G., Meyer, M., Forssmann, W.G., & Nehls, M. (1999) Structural and phylogenetic characterization of human SLURP-1, the first secreted mammalian member of the Ly-6/uPAR protein superfamily. Protein Sci., 8, 810-819. #12704

  11. Adesida, A.B., Aojula, R.R., Aojula, H.S., & Clarke, D.J. (1999) Nonepitopic antibody binding sequence: implications in screening and development of peptide vaccines. Vaccine, 18, 315-320. #13897

  12. Adinolfi, M., Barone, G., De Napoli, L., Guariniello, L., Iadonisi, A., & Piccialli, G. (1999) Solid phase glycosidation of oligonucleotides. Tetrahedron Lett., 40, 2607-2610. #12621

  13. Afshar, M., Prescott, C.D., & Varani, G. (1999) Structure-based and combinatorial search for new RNA-binding drugs. Curr. Opin. Biotechnol., 10, 59-63. #12705

  14. Agrafiotis, D.K., & Lobanov, V.S. (1999) An efficient implementation of distance-based diversity measures based on k-d trees. Journal of Chemical Information and Computer Sciences, 39, 51-58. #12298

  15. Agrafiotis, D.K., Myslik, J.C., & Salemme, F.R. (1999) Advances in diversity profiling and combinatorial series design. Mol. Diversity, 4, 1-22. #12921

  16. Ahlberg, C. (1999) Realizing the potential of complex databases. Scientific Computing and Instrumentation, 16, 3. #15398

  17. Ajay, Bemis, G.W., & Murcko, M.A. (1999) Designing libraries with CNS activity. J. Med. Chem., 42, 4942-4951. #13898

  18. Akerblom, E.B. (1999) Six new photolabile linkers for solid phase synthesis. 2. Coupling of various building blocks and photolytic cleavage. Mol. Diversity, 4, 53-69. #12923

  19. Al-Obeidi, F., & Ostrem, J.A. (1999) Factor Xa inhibitors. Exp. Opin. Ther. Patents, 9, 931-953. #13469

  20. Albericio, F., Frieden, A., del Fresno, M., Royo, M., Alsina, J., Jensen, K.J., Kates, S.A. & Barany, G. (1999) Solid-phase synthesis of "head-to-tail" cyclic and C-terminal modified peptides. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries. (pp. 7-10). Mayflower Scientific Limited, Birmingham. #13450

  21. Albrecht, M., Blau, O., & Frohlich, R. (1999) An expansible metalla-cryptand as a component of a supramolecular combinatorial library formed from di(8-hydroxyquinoline) ligands and gallium(III) or zinc(II) ions. Chem. Eur. J., 5, 48-56. #12301

  22. Alfaro-Lopez, J., Okayama, T., Hosohata, K., Davis, P., Porreca, F., Yamamura, H.I., & Hruby, V.J. (1999) Exploring the structure-activity relationships of [1-(4-tert-butyl-3'-hydroxy)benzhydryl-4-benzylpiperazine] (SL-3111), a high-affinity and selective delta-opioid receptor nonpeptide agonist ligand. J. Med. Chem., 42, 5359-5368. #13899

  23. Ali, T., Chauhan, K.K., & Frost, C.G. (1999) Indium triflate: An efficient catalyst for hetero Diels-Alder reactions. Tetrahedron Lett., 40, 5621-5624. #13400

  24. Alsina, J., Jensen, K.J., Albericio, F., & Barany, G. (1999) Solid-phase synthesis with tris(alkoxy)benzyl backbone amide linkage (BAL). Chem. Eur. J., 5, 2787-2795. #14915

  25. Altman, R.K., Schwope, I., Sarracino, D.A., Tetzlaff, C.N., Bleczinski, C.F., & Richert, C. (1999) Selection of modified oligonucleotides with increased target affinity via MALDI-monitored nuclease survival assays. Journal of Combinatorial Chemistry, 1, 493-508. #13901

  26. Altreuter, D.H., & Clark, D.S. (1999) Combinatorial biocatalysis: Taking the lead from Nature. Curr. Opin. Biotechnol., 10, 130-136. #12706

  27. Ambler, J., Baker, E., Bentley, D., Brown, L., Butler, K., Butler, P., Farr, D., Dunnet, K., Le Grand, D., Hayler, J., Janus, D., Jones, D., Menear, K., Mercer, M., Smith, G., Talbot, M., & Tweed, M. (1999) Studies towards the identification of potent, selective and bioavailable thrombin inhibitors. Bioorg. Med. Chem. Lett., 9, 737-742. #15662

  28. Anderson, R.C., Lin, M., & Shapiro, M.J. (1999) Affinity NMR: Decoding DNA binding. Journal of Combinatorial Chemistry, 1, 69-72. #12041 (Available on Internet)

  29. Andersson, P.M., Linusson, A., Wold, S., Sjostrom, M., Lundstedt, T., & Norden, B. (1999) Design of small libraries for lead exploration. Molecular Diversity in Drug Design, 197-220. #14918

  30. Andres, C.J., Swann, R.T., Grant-Young, K., D'Andrea, S.V., & Deshpande, M.S. (1999) A novel cleavage protocol for use with Rf-encoded split pool synthesis technology: Product cleavage and collection in standard 96 well format. Comb. Chem. High Throughput Screening, 2, 29-32. #12848

  31. Andres, C.J., Denhart, D.J., Deshpande, M.S., & Gillman, K.W. (1999) Recent advances in the solid phase synthesis of drug-like heterocyclic small molecules. Comb. Chem. High Throughput Screening, 2, 191-210. #13903

  32. Andrus, M.B., Turner, T.M., Asgari, D., & Li, W.K. (1999) The synthesis and evaluation of a solution-phase indexed combinatorial library of non-natural polyenes for multidrug resistance reversal. J. Org. Chem., 64, 2978-2979. #12925

  33. Angell, Y.M., Jensen, K.J., Gross, C.M. & Barany, G. (1999) Solid-phase synthesis of peptide nucleic analogue (PNA) sequences taken to new lengths. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries. (pp. 59-62). Mayflower Scientific Limited, Birmingham. #13460

  34. Angell, Y.M., Raman, P., Flentke, G.R. & Rich, D.H. (1999) Solid phase synthesis of cyclosporins involving on-resin and solution cyclizations. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries. (pp. 135-138). Mayflower Scientific Limited, Birmingham. #13664

  35. Ankersen, M., Hansen, B.S., Hansen, T.K., Lau, J., Peschke, B., Madsen, K., & Johansen, N.L. (1999) Demonstration of the strength of focused combinatorial libraries in SAR optimisation of growth hormone secretagogues. Eur. J. Med. Chem., 34, 783-790. #13904

  36. Antel, J. (1999) Integration of combinatorial chemistry and structure-based drug design. Curr. Opin. Drug. Disc. Develop., 2, 224-233. #13396

  37. Antonenko, V.V. (1999) Automation in combinatorial chemistry. In Anonymous, Combinatorial Chemistry and Technology: Principles, Methods, and Applications. (pp. 205-232). #13471

  38. Aoki, Y., & Kobayashi, S. (1999) Development of a reductive alkylation method using p-benzyloxybenzylamine (BOBA) resin for the synthesis of N-alkylated amides. Journal of Combinatorial Chemistry, 1, 371-372. #13650

  39. Apostolakis, J., & Caflisch, A. (1999) Computational ligand design. Comb. Chem. High Throughput Screening, 2, 91-104. #12852

  40. Appel, J.R., Johnson, J., Narayanan, V.L., & Houghten, R.A. (1999) Identification of novel antitumor agents from mixture-based synthetic combinatorial libraries using cell-based assays. Mol. Diversity, 4, 91-102. #12926

  41. Appleton, T. (1999) Combinatorial chemistry and HTS: Feeding a voracious process. Drug Disc. Today, 4, 398-400. #13473

  42. Aramburu, J., Yaffe, M.B., Lopez-Rodriguez, C., Cantley, L.C., Hogan, P.G., & Rao, A. (1999) Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A. Science, 285, 2129-2133. #13907

  43. Archer, R. (1999) The drug discovery factory: An inevitable evolutionary consequence of high-throughput parallel processing. Nat. Biotech., 17, 834-834. #14712

  44. Argyris, E.G., Vanderkooi, J.M., Venkateswaran, P.S., Kay, B.K., & Paterson, Y. (1999) The connection domain is implicated in metalloporphyrin binding and inhibition of HIV reverse transcriptase. Journal of Biological Chemistry, 274, 1549-1556. #12927

  45. Arsequell, G., Espuna, G., Valencia, G., Barluenga, J., Perez Carlon, R., & Gonzalez, J.M. (1999) Selective solid-phase iodination of phenolic groups with bis(pyridine)iodonium (I) tetrafluoroborate. Tetrahedron Lett., 40, 7279-7282. #13775

  46. Atiq-ur-Rehman, Li, C., Budge, L.P., Street, S.E., & Savage, P. (1999) Preparation of amino acid-appended cholic acid derivatives as sensitizers of gram-negative bacteria. Tetrahedron Lett., 40, 1865-1868. #12606

  47. Attanasi, O.A., Filippone, P., Guidi, B., Hippe, T., Mantellini, F., & Tietze, L.F. (1999) First preparation and reaction of polymer-bound 1,2-diaza-1,3-butadienes. A convenient entry to 4-triphenylphosphoranylidene-4,5-dihydropyrazol-5-ones. Tetrahedron Lett., 40, 9277-9280. #13879

  48. Atwell, S., & Wells, J.A. (1999) Selection for improved subtiligases by phage display. Proc. Natl. Acad. Sci. USA, 96, 9497-9502. #13474

  49. Aubagnac, J.L., Enjalbal, C., Drouot, C., Combarieu, R., & Martinez, J. (1999) Imaging time-of-flight secondary ion mass spectrometry of solid-phase peptide syntheses. J. Mass Spectrom., 34, 749-754. #13475

  50. Aubagnac, J.L., Amblard, M., Enjalbal, C., Subra, G., Martinez, J., Durand, P., & Renaut, P. (1999) Identification of synthetic by-products in combinatorial libraries using high performance liquid chromatography-electrospray ionization mass spectrometry. Comb. Chem. High Throughput Screening, 2, 289-296. #13909

  51. Augeri, D.J., Janowick, D., Kalvin, D., Sullivan, G., Larsen, J., Dickman, D., Ding, H., Cohen, J., Lee, J., Warner, R., Kovar, P., Cherian, S., Saeed, B., Zhang, H., Tahir, S., Ng, S.C., Sham, H., & Rosenberg, S.H. (1999) Potential and orally bioavailable noncysteine-containing inhibitors of protein farnesyltransferase. Bioorg. Med. Chem. Lett., 9, 1069-1074. #15613

  52. Babaev, E.V. (1999) Organic synthesis and combinatorial chemistry [Russian]. Khimiya Geterotsiklicheskikh Soedinenii, 714-716. #13476

  53. Bagno, A., Bicciato, S., Di Bello, C. & Bonora, G.M. (1999) Automated liquid-phase biopolymer synthesis. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries. (pp. 51-54). Mayflower Scientific Limited, Birmingham. #13458

  54. Bailey, C., Baker, E., Hayler, J., & Kane, P. (1999) Amidine protection for solution phase library synthesis. Tetrahedron Lett., 40, 4847-4850. #13113

  55. Bakhtiar, R., & Ochiai, E.I. (1999) Pharmacological applications of inorganic complexes. General Pharmacology, 32, 525-540. #12930

  56. Baldwin, J. J., Burbaum, J., and Sigal, N. H. Combinatorial chemistry: Part of the evolution in drug discovery. In: Anonymous. (Eds.) Kluwer Academic/Plenum Publishers, New York p.71 Current Trends in Organic Synthesis. #15687OLD

  57. Bankaitis-Davis, D., Beaton, G., Bjergarde, K., Callaway, W., Cook, A., Curtis, M., Herrera, C., Huang, L., Josey, J., Munson, M. & Tarlton, C. (1999) Flexible approaches for high-speed synthesis: A multiple platform strategy. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries. (pp. 257-258). Mayflower Scientific Limited, Birmingham. #13689

  58. Barn, D.R., & Morphy, J.R. (1999) Solid-phase synthesis of cyclic imides. Journal of Combinatorial Chemistry, 1, 151-156. #12700

  59. Barn, D.R., Bom, A., Cottney, J., Caulfield, W.L., & Morphy, J.R. (1999) Synthesis of novel analogues of the delta opioid ligand SNC-80 using AlCl3-promoted aminolysis. Bioorg. Med. Chem. Lett., 9, 1329-1334. #15614

  60. Barrett, A.G.M., Cramp, S.M., & Roberts, R.S. (1999) ROMP-spheres: A novel high-loading polymer support using cross metathesis between vinyl polystyrene and norbornene derivatives. Organic Letters, 1, 1083-1086. #14930

  61. Barron, A.E., & Zuckermann, R.N. (1999) Bioinspired polymeric materials: In-between proteins and plastics. Curr. Opin. Chem. Biol., 3, 681-687. #15486

  62. Barry, J.F., Davis, A.P., Perez-Payan, M.N., Elsegood, M.R.J., Jackson, R.F.W., Gennari, C., Piarulli, U., & Gude, M. (1999) A trifunctional steroid-based scaffold for combinatorial chemistry. Tetrahedron Lett., 40, 2849-2852. #12624

  63. Bartlett, P.A., & Joyce, G.F. (1999) Combinatorial chemistry: The search continues - Editorial overview. Curr. Opin. Chem. Biol., 3, 253-255. #12932

  64. Bayada, D.M., Hamersma, H., & van, G., V. (1999) Molecular diversity and representativity in chemical databases. Journal of Chemical Information and Computer Sciences, 39, 1-10. #12308

  65. Becker, J.A.J., Wallace, A., Garzon, A., Ingallinella, P., Bianchi, E., Cortese, R., Simonin, F., Kieffer, B.L., & Pessi, A. (1999) Ligands for kappa-opioid and ORL1 receptors identified from a conformationally constrained peptide combinatorial library. Journal of Biological Chemistry, 274, 27513-27522. #13915

  66. Becker, J.A.J., Wallace, A., Garzon, A., Ingallinella, P., Bianchi, E., Cortese, R., Simonin, F., Keiffer, B.L., & Pessi, A. (1999) Ligands for kappa-opioid and ORL1 receptors identified from a conformationally constrained peptide combinatorial library (vol 274, pg 27513, 1999). Journal of Biological Chemistry, 274, 33177-33177. #13914

  67. Begent, R.H.J. (1999) Targeting cancer therapy. British Journal of Cancer, 80, -109. #13479

  68. Bein, T. (1999) Efficient assays for combinatorial methods for the discovery of catalysts. Angew. Chem. Int. Ed., 38, 323-326. #12590

  69. Bemis, G.W., & Murcko, M.A. (1999) Properties of known drugs. 2. Side chains. J. Med. Chem., 42, 5095-5099. #13918

  70. Benigni, R., Gallo, G., Giorgi, F., & Giuliani, A. (1999) On the equivalence between different descriptions of molecules: Value for computational approaches. Journal of Chemical Information and Computer Sciences, 39, 575-578. #12935

  71. Berg, T., Simeonov, A., & Janda, K.D. (1999) A combined parallel synthesis and screening of macrocyclic lanthanide complexes for the cleavage of phospho di- and triesters and double-stranded DNA. Journal of Combinatorial Chemistry, 1, 96-100. #12034 (Available on Internet)

  72. Bergbreiter, D.E. (1999) Alternative polymer supports for organic chemistry. Med. Res. Rev., 19, 439-450. #13919

  73. Berger, C., Martin, N., Collin, S., Gijs, L., Khan, J.A., Piraprez, G., Spinnler, H.E., & Vulfson, E.N. (1999) Combinatorial approach to flavor analysis. 2. Olfactory investigation of a library of S-methyl thioesters and sensory evaluation of selected components. J. Agric. Food Chem., 47, 3274-3279. #13481

  74. Bergnes, G., Gilliam, C.L., Boisclair, M.D., Blanchard, J.L., Blake, K.V., Epstein, D.M., & Pal, K. (1999) Generation of an UGI library of phosphate mimic-containing compounds and identification of novel dual specific phosphatase inhibitors. Bioorg. Med. Chem. Lett., 9, 2849-2854. #13920

  75. Berk, S.C., Rohrer, S.P., Degrado, S.J., Birzin, E.T., Mosley, R.T., Hutchins, S.M., Pasternak, A., Schaeffer, J.M., Underwood, D.J., & Chapman, K.T. (1999) A combinatorial approach toward the discovery of non-peptide, subtype-selective somatostatin receptor ligands. Journal of Combinatorial Chemistry, 1, 388-396. #13654

  76. Berkessel, A., & Herault, D.A. (1999) Discovery of peptide-zirconium complexes that mediate phosphate hydrolysis by batch screening of a combinatorial undecapeptide library. Angew. Chem. Int. Ed., 38, 102-105. #12218

  77. Berl, V., Huc, I., Lehn, J.M., DeCian, A., & Fischer, J. (1999) Induced fit selection of a barbiturate receptor from a dynamic structural and conformational/configurational library. Eur. J. Org. Chem., 3089-3094. #14942

  78. Bernard, P., Berthon, J.Y., & Chretien, J.R. (1999) Computer-aided molecular selection and design of natural bioactive molecules. Curr. Opin. Drug. Disc. Develop., 2, 213-223. #13395

  79. Berteina, S., De Mesmaeker, A., & Wendeborn, S. (1999) Functionalization via radical cyclization of cyclohexenediol derivatives bound to polystyrene. Synlett, 1121-1123. #13482

  80. Bhagwat, S.S., Manning, A.M., Hoekstra, M.F., & Lewis, A. (1999) Gene-regulating protein kinases as importatnt anti-inflamatory targets. Drug Disc. Today, 4, 472-479. #15491

  81. Bhat, A.S., Whetstone, J.L., & Brueggemeier, R.W. (1999) Novel synthetic routes suitable for constructing benzopyrone combinatorial libraries. Tetrahedron Lett., 40, 2469-2472. #12626

  82. Bianchi, A.A., & Baneyx, F. (1999) Stress responses as a tool to detect and characterize the mode of action of antibacterial agents. Appl. Environ. Microbiol., 65, 5023-5027. #13921

  83. Biederman, K.J., Lee, H., Haney, C.A., Kaczmarek, M., & Buettner, J.A. (1999) Combinatorial peptide on-resin analysis: Optimization of static nanoelectrospray ionization technique for sequence determination. J. Pept. Res., 53, 234-243. #12859

  84. Birr, C. (1999) Organic synthetic methodology extensions forgotten in peptide science. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries. (pp. 75-84). Mayflower Scientific Limited, Birmingham. #13464

  85. Bjorling, E., von Garrelts, E., Morner, A., Ehnlund, M., & Persson, M.A.A. (1999) Human neutralizing human immunodeficiency virus type 2-specific Fab molecules generated by phage display. J. Gen. Virol., 80, -1993. #13483

  86. Blackburn, C., Barany, G., Albericio, F. & Kates, S.A. (1999) Handles for solid-phase chemistry: Progress from peptide to small molecule synthesis. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries. (pp. 31-38). Mayflower Scientific Limited, Birmingham. #13455

  87. Blackburn, C. & Kates, S.A. (1999) Homodetic cyclic peptides via solid phase synthesis. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries. (pp. 129-134). Mayflower Scientific Limited, Birmingham. #13663

  88. Blettner, C.G., Konig, W.A., Ruhter, G., Stenzel, W., & Schotten, T. (1999) Parallel synthesis of poly(ethylene)glycol supported biaryl benzimidazoles and imidazopyridines. Synlett, 307-310. #15615

  89. Blettner, C.G., Schotten, T., Stenzel, W. & Konig, W.A. (1999) PEG polymer supported liquid phase parallel synthesis of Suzuki and Heck products. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries. (pp. 263-266). Mayflower Scientific Limited, Birmingham. #13690

  90. Blitz, J., & Little, C.B. (1999) Fundamental and applied aspects of chemically modified surfaces. The Royal Society of Chemistry, Cambridge. ISBN 085404714X #14720

  91. Blom, K.F., Larsen, B.S., & McEwen, C.N. (1999) Determining affinity-selected ligands and estimating binding affinities by online size exclusion chromatography/liquid chromatography-mass spectrometry. Journal of Combinatorial Chemistry, 1, 82-90. #12032 (Available on Internet)

  92. Blondelle, S.E. & Houghten, R.A. (1999) Synthetic combinatorial libraries: A new tool for antimicrobial agent discovery. In S. Grabley & R. Thiericke (Eds.), Drug discovery from nature. (pp. 311-319). #12909

  93. Blondelle, S.E., Takahashi, E., Robles, B.L., Houghten, R.A. & Perez-Paya, E. (1999) Design of catalytic mimics for the decarboxylation of oxaloacetate using synthetic combinatorial libraries. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries. (pp. 163-166). Mayflower Scientific Limited, Birmingham. #13669

  94. Blondelle, S.E., Crooks, E., Ostresh, J.M., & Houghten, R.A. (1999) Mixture-based heterocyclic combinatorial positional scanning libraries: Discovery of bicyclic guanidines having potent antifungal activities against Candida albicans and Cryptococcus neoformans. Antimicrob. Agents Chemother., 43, 106-114. #12711

  95. Boeijen, A., & Liskamp, R.M.J. (1999) Solid-phase synthesis of oligourea peptidomimetics. Eur. J. Org. Chem., 2127-2135. #14947

  96. Boger, D.L., Jiang, W.Q., & Goldberg, J. (1999) Convergent solution-phase combinatorial synthesis with multiplication of diversity through rigid biaryl and diarylacetylene couplings. J. Org. Chem., 64, 7094-7100. #13792

  97. Boger, D.L., Goldberg, J., & Andersson, C.M. (1999) Solution phase combinatorial synthesis of biaryl libraries employing heterogeneous conditions for catalysis and isolation with size exclusion chromatography for purification. J. Org. Chem., 64, 2422-2427. #12860

  98. Boguslavsky, J. (1999) Need protein? Organic chemistry holds the key. Drug. Dis. Develop., 30-33. #12914

  99. Bohlmann, J., Phillips, M., Ramachandiran, V., Katoh, S., & Croteau, R. (1999) cDNA cloning, characterization, and functional expression of four new monoterpene synthase members of the Tpsd gene family from grand fir (Abies grandis). Arch. Biochem. Biophys., 368, 232-243. #13793

  100. Bohm, H.J., Banner, D.W., & Weber, L. (1999) Combinatorial docking and combinatorial chemistry: Design of potent non-peptide thrombin inhibitors. J. Comput. Aid. Molec. Design, 13, 51-56. #12712

  101. Boisnard, S., Chastanet, J., & Zhu, J. (1999) A high throughput synthesis of aryl triflate and aryl nonaflate promoted by a polymer supported base (PTBD). Tetrahedron Lett., 40, 7469-7472. #13767

  102. Boivin, J., Pothier, J., & Zard, S.Z. (1999) A flexible, convergent approach to piperidines, pyridines, azepines, and related derivatives. Tetrahedron Lett., 40, 3701-3704. #14208

  103. Boiziau, C., Dausse, E., Yurchenko, L., & Toulme, J.J. (1999) DNA aptamers selected against the HIV-1 trans-activation-responsive RNA element form RNA-DNA kissing complexes. Journal of Biological Chemistry, 274, 12730-12737. #12937

  104. Boldi, A.M., Johnson, C.R., & Eissa, H.O. (1999) Solid-phase library synthesis of triazolopyridazines via [4+2] cycloadditions. Tetrahedron Lett., 40, 619-622. #12220

  105. Bolton, G.L., & Hodges, J.C. (1999) Solid-phase synthesis of substituted benzazepines via intramolecular Heck cyclization. Journal of Combinatorial Chemistry, 1, 130-133. #12697

  106. Bongardt, P., Gerster, M. & Bayer, E. (1999) Synthesis and characterization of very short peptide-oligonucleotide conjugates used for the transport of antisense oligonucleotides. In R. Epton (Ed.), Innovation and Perspectives in Solid Phase Synthesis & Combinatorial Libraries. (pp. 267-270). Mayflower Scientific Limited, Birmingham. #13691

  107. Booth, R.J., & Hodges, J.C. (1999) Solid-supported reagent strategies for rapid purification of combinatorial synthesis products. Account. Chem. Res., 32, 18-26. #12284

  108. Bordusa, F., Dahl, C., Jakubke, H.D., Burger, K., & Koksch, B. (1999) Synthesis of alpha-fluoroalkyl substituted peptides via enzymatic fragment condensation. Tetrahedron-Asymmetry, 10, 307-313. #12713

  109. Borman, S. (1999) Modified T-cell receptors produced as a library. C&EN, 77, 34-34. #13097

  110. Borman, S. (1999) Genomics rises to drug discovery challenge. C&EN, 77, 59-68. #13098

  111. Borman, S. (1999) Reducing time to drug discovery. Recent advances in solid-phase synthesis, informatics, and high-throughput screening suggest combinatorial chemistry is coming of age. C&EN, 77, 33-48. #12854

  112. Borman, S. (1999) New phage display format developed. C&EN, 77, 6-6. #13096

  113. Bottoli, A.P.F., Kertesz-Chaloupkova, K., Boulianne, R.P., Granado, J.D., Aebi, M., & Kues, U. (1999) Rapid isolation of genes from an indexed genomic library of C-cinereus in a novel pab1+ cosmid. J. Microbiol. Methods, 35, 129-141. #12628

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