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L003 Synthesis of β-turn mimics without stereogenic carbons: expanding the modular approach for diversity-oriented synthesis of tetrasubstituted benzotriazepinones
Xiaozheng Wei, Sarah-Maude Harvey, Debora Iaculli, Steven Ballet, William D. Lubell
L005 Fundamental aspects of SPPS and the Green future
Stephen Kent
L020 tCAP conjugate: an affinity peptide-based antibody conjugation system to generate highly functional antibody
Yuji Ito
YIF02 Bimodal use of chiral α-Trifluoromethylalanine in Aib Foldamers: study of the position impact towards the helical screw-sense preference
Nathan Picois, Lizeth Bodero, Pierre Milbeo, Thierry Brigaud, Grégory Chaume
YIF09 Designed cyclic peptides as inhibitors of amyloid self-assembly and cross-seeding of amyloid-beta peptide and islet amyloid polypeptide
Beatrice Dalla Volta, Melanie Roth, Yuan Tian, Alessia Calzi, Jürgen Bernhagen, Aphrodite Kapurniotu
YIF13 Targeting West Nile virus replicases: NS3 and heterodimers inhibitors
Daniele Volpin, Cristina Peggion, Riccardo Rigo, Matia Sturlese
YIF20 Short Catalytic Peptides for Carbon Dioxide Sequestration
Kalpana Kumari, Vibin Ramakrishnan
YIF21 Bioactive Self-assembled Peptide Hydrogels for 3D Cancer Model Applications
Burcu Sırma Tarım, Sedef Tamburacı, Ayben Top
P1002 Convergent synthesis of peptidomimetic based on a chloroalkene dipeptide isostere and its application to inhibition against amyloid β aggregation
Takuya Kobayakawa, Chika Azuma, Kenichi Yamamoto, Kohei Tsuji, Hirokazu Tamamura
P1003 Optimization of IEDDA reaction parameters
Rasheda Aktar Samiha, Samir Das, Arundhati Nag
P1004 Identification of reactivity hotspots at the interfaces of protein–protein interactions
Nathalie M. Grob, Clint Remarcik, Simon L. Rössler, Jeffrey Y. K. Wong, John C. K. Wang, Jason Tao, Corey L. Smith, Andrei Loas, Stephen Buchwald, Dan Eaton, Magdalena Preciado López, Bradley Pentelute
P1005 Using N-acylation as a disulfide lock simplifies chemical protein synthesis
Vincent Diemer, Vangelis Agouridas, Benoît Snella, Rémi Desmet, Oleg Melnyk
P1007 Synthesis of Peptide Hydrazides: Hydrazone Resin vs. Hydrazine 2CT Resin
Maria Leko, Polina Filippova, Karin Rustler, Thomas Bruckdorfer, Sergey Burov
P1009 Facilitating the access to repeat proteins by a novel water-compatible oligomerization process
Eliott Roy, Oleg Melnyk, Vincent Diemer
P1012 Technetium-99m tricarbonyl complexes containing amino acid derivatives for cancer imaging
João D.G. Correia, Rúben D.M. Silva, Cristina P. Matos, Catarina I.G. Pinto, Joana F. Guerreiro, Lurdes Gano, Filipa Mendes
P1013 Development of methodology for late-stage acylation of threonine residue enabled by chemoselective acyl transfer followed by desulfurization
Daiki Sato, Chiho Shinozaki, Masaya Denda, Akira Otaka
P1014 Towards the total synthesis of the bacteriocin Nisin A on solid support
Ilia Perov, Bethan Donnelly, Tyler Mallett, John Vederas
P1015 Protein semi-synthetic approach to probe C-terminal hyperphosphorylation of the Alzheimer-relevant protein Tau
Bingjia Yan, Léa EI Hajjar, Wenyi Lia, Caroline Smet-Nocca, Christian P. R. Hackenberger
P1016 Structural Optimization Study Leading to Orally Bioavailable Cyclic Peptides Inhibiting an Intracellular Tough Target
Mikimasa Tanada, Ryuji Hayashi, Mirai Kage, Atsushi Ohta, Hitoshi Iikura,Takuya Shiraishi
P1017 Chemical Engineering of Artificial Transcription Factors
Omer Harel, Xiaoxi Lin, Muhammad Jbara
P1018 Peptides Targeting DNA Four-Way Junctions
Eleanor Ivens, Andrew Beekman, Mark Searcey
P1019 C-Glycosylation of Aromatic Amino Acids by Pd-Catalyzed Cross-Coupling
Calvin Matula, Norbert Sewald
P1020 Efficient Peptide Thioester Synthesis from Hydrazides Using Near-Stoichiometric Thiol Quantities
Julie Di Adamo, Nathalie Ollivier, Vincent Diemer, Oleg Melnyk
P1021 Electrostatic Assistance of NCL Catalysis by 4-Mercaptophenylacetic Acid
Nathalie Ollivier, Eliott Roy, Remi Desmet, Vangelis Agouridas, Vincent Diemer, Oleg Melnyk
P1022 An efficient strategy to bioconjugate disulfide-rich peptides via thiol-maleimide chemistry while preserving their bridging pattern
Lylia Azzoug, Hervé Meudal, Karine Loth, Séverine Morisset-Lopez, Carlo Pifferi,Vincent Aucagne
P1023 Auxiliaries in Native Chemical Ligation: Exploring the Reactivity Landscape with new Scaffolds
Sebastian Trunschke, Antonia Feida, Oliver Seitz
P1025 Superfast Desulfurization for Protein Chemical Synthesis and Modification
Zhenquan Sun, Yihui Cao, Xuechen Li
P1026 An iron-catalyzed protein desulfurization method reminiscent of aquatic chemistry
Rémi Desmet, Céline Wichlacz, Aurélie Tasiemski, Vangelis Agouridas, Oleg Melnyk
P1027 Chemoselective P-S coupling of aminophospholes to peptides under mild conditions
Emmanuelle Rémond, Laure Liénart, Miyanou Rosales-Hurtado, Sébastien Clément, Jean-Alain Fehrentz, Jean-Louis Banères, Florine Cavelier
P1029 Flow – SPPS towards greener and more efficient peptide manufacturing
Oliver Kracker, Eike-Fabian Sachs
P1030 Design of Experiments as Powerful Tool for Peptide Cleavage Development
Teresa Friedrichs, Alexander P. Galow
P1031 Synthetic combinatorial OPA-cyclic peptide library
Kin Nam Adrian Chu, Carina Hey Pui Cheung, Xuechen Li
P1032 Direct synthesis of peptidomimetics containing non-coded amino acids via photocatalytic carbamoylation reaction
T. Gandini, M. L. Gelmi, R. Bucci
P1034 Thiol-yne Mediated Macrocyclisation and Derivatisation Strategies
Conor Williams, Dearbhla Tully, Susannah H. Calvert, Joanna F. McGouran, Eoin M. Scanlan
P1036 Synthesis and biological activity of ultra-short antimicrobial peptides bearing a novel noncoded amino acid
Barbara Biondi, Fernando Formaggio, Cristina Peggion, Andrea Schivo, Teodora Calin, Simona Oancea, Emma Khachatryan, Liana Hayriyan, Ashot Saghyan, Anna Mkrtchyan
P1037 Evaluation of the stability of oxytocin and vasopressin under oxidative stress conditions
Stefano Tartaggia, Claudia Honisch, Martina Rotondo, Paolo Ruzza
P1038 Biocatalytic Synthesis of Dihalogenated Tryptophan Derivatives
Bjarne Scharkowski, Nicolai Montua, Norbert Sewald
P1039 Silicon-containing amino acids for 18F labeling of neurotensin analogues targeting NTS1 receptor
Miyanou Rosales Hurtado, Emmanuelle Rémond, Delphine Vimont, Alexis Reinbold, Elif Hindié, Clément Morgat, Florine Cavelier
P1042 Preclinical Development of Myrcludex B Derivatives: Physicochemical Properties
Tyra Christian, Sabrina Wohlfart, Christian Kleist, Philipp Uhl, Stephan Urban, Walter Mier
P1044 Exploring the structure-function relationship of heme binding to blood coagulation factor VIII based on peptide models
Lorena Kröner, Diana Imhof, Marie-T. Hopp
P1046 Site-specific post-translational modifications of Tau4
Miriam M. K. Preissler, Dominik Vogl, Christian F. W. Becker
P1047 Synthesis of the natural peptide product Fusahexin
Carmen Bäuerlein, Armin Geyer
P1049 Organocatalytic Surfactants for Direct Asymmetric Aldol Reactions in Aqueous Media
Susanta Kumar Behera, Ramesh Ramapanicker
P1050 O-to-O Acyl Transfer for Epimerization-free Peptide C-terminal Salicylaldehyde Ester Synthesis
Zhixiang Zhong, Wang Xia, Bing-Wen Li, Han Liu, Zhi-Xiang Yu, Xuechen Li
P1051 New electrochemical method for Arylation of Cysteine containing peptides
Shen Linhua, Olivier Monasson, Elisa Peroni, Franck Le Bideau, Samir Messaoudi
P1052 N-Aminoimidazol-2-one Peptide Mimic Tools for Deciphering Active Conformations
Yousra Hamdane, Pradeep Chauhan, Suresh Vutla, Darince Truong, William D. Lubell
P1054 Ring Pucker Control in β-Prolines
Nassim Maarouf Mesli, William D. Lubell
P1055 Nature-Inspired Gallinamides Are Potent Antischistosomal Agents: Inhibition of the cathepsin B1 Protease Target and Binding Mode Analysis
P. Spiwokova, M. Horn, L. Maresova, J. Fanfrlik, A. Jilkova, P. Fajtova, A. Leontovyc, R. Houstecka, L. Bielikova, J. Brynda, M. Chanova, H. Mertlikova-Kaiserova, E. Caro-Diaz, J. Almaliti, N. El-Sakkary, W.H. Gerwick, C.R. Caffrey, M. Mares
P1056 Study on interactions of LL-37 human cathelicidin peptide fragment with Cu(II) ion
Jakub Brzeski, Dariusz Wyrzykowski, Bogusław Pilarski, Joanna Makowska
P1058 Peptide stapling - application in antibacterial therapies
Monika Wojciechowska, Julia Macyszyn, Michal Burmistrz, Joanna Miszkiewicz, Malgorzata Lobka, Joana Trylska
P1059 Translocation-Enhancing Peptides: FacilitateTransport of Molecules and Lipid Scrambling
Ladislav Bartoš, Robert Vácha
P1062 Antimicrobial activity of Histatin 5 based metallopeptides
Gabriela Vieira Silva Zolin, Renan Lira de Farias, Saulo Santesso Garrido
P1063 De novo design of miniproteins binding to PD-L1
Juan Lizandra Pérez, Natalia Miodowska, Łukasz Berlicki
P1064 Metal complexes of ATCUN-like peptides for sequence-specific DNA cleavage
Ivan N. Unksov, Lena K. Müller, Hanna Zdhannova, Alexander Gräwe, Joshua Stahl, Viktor Stein, Daniel Tietze, Alesia A. Tietze
P1067 Development of peptide-based inhibitors against β-catenin using in silico approach
Minami Fujita, Amika Kikuchi, Kyohei Arita, Takashi Misawa, Yosuke Demizu
P1068 An Intracellular Cyclisation Screen Generates Short Helical Peptide Inhibitor of Alpha Synuclein Aggregation
Scott G. Allen, Richard M. Meade, Robert J. Williams, Jody M. Mason
P1070 Synthesis and study of modified Temporin analogs with unnatural amino acids Citrulline and Ornithine as potential antibacterial agents
Nelly Georgieva, Dilyana Dimitrova, Tsvetelina Foteva, Veronika Nemska, Dancho Danalev
P1071 New unique analogs of anorexigenic cocaine- and amphetamine-regulated transcript peptide
Andrea Pačesová, Vilém Charvát, Miroslava Blechová, Blanka Železná, Jaroslav Kuneš, Lenka Maletínská
P1072 Antibacterial and anti-biofilm activity of branched peptides derived from antimicrobial peptides
Eva Tollapi, Alessandro Rencinai, Giada Meogrossi, Silvia Scali, Chiara Falciani
P1073 AMP32: a short cyclic peptide as an environmentally friendly alternative to counteract late blight symptoms in crops
Elena Marone Fassolo, Demetrio Marcianò, Stefano Rosa, Lucia Feni, Vaibhav Srivastava, Andrea Tagliani, Silvia Laura Toffolatti, Sara Pellegrino, Vincent Bulone, Simona Masiero, Paolo Pesaresi
P1075 Water-soluble longibramide E analogs: synthesis and antibacterial activity
Renato B. Pereira, Ana Gomes, Mariana Ferreira, Paula Gameiro, Paula Gomes
P1076 Generation of a Peptide Library from human Bone Marrow for the discovery and identification of novel bio active bone-marrow derived peptides
Nico Preising, Armando A. Rodriguez, Merve Karacan, Sebastian Wiese, Dennis Freisem, Fabian Zech, Dietmar Thal, Konstantin Sparrer, Jan Münch, Frank Kirchhoff, Ludger Ständker
P1079 Synthesis and antibacterial activity of new analogues of Aurein 1.2
Nora Angelova, Tsvetelina Foteva, Veronica Nemska, Nelly Georgieva, Dancho Danalev, Emilia Naydenova
P1080 Tackling antibiotic resistance by blocking signalling pathways
Rachel A. Johnson, Susanne Gebhard, Jody M. Mason
P1081 Synthesis and evaluation of β-secretase inhibitory activity of new Galantamine derivatives comprising peptide moiety
Emilia Naydenova, Lyubomir T. Vezenkov ,Valentin Lozanov, Daniela S. Tsekova
P1082 Searching for biologically active peptide fragments of hACE2 interacting with the S1 protein of the SARS-CoV-2 virus
Aleksandra Czerchawy, Manoj Kumar Muthyala, Beata Kolesińska
P1084 Synthesis of Aza-Amanitins to Enhance Cytotoxicity for Targeted Cancer Therapeutics
Kayla C. Newell, F. Cruz Custodinho, Juliette Froelich, Katherine Bessai, Cassandra M. Sgarbi, David M. Perrin
P1085 In situ mechanistic insight to antibacterial action of membrane-incising β-peptide lamellae
Kamal el Battioui, Imola Cs. Szigyártó, Sohini Chakraborty, Judit Tóth, Dániel Molnár, Tünde Juhász, Loránd Románszki, Andrea Bodor, Kata Horváti, István Mándity, Zoltán Varga, Judith Mihály, Csenge Lilla Szabó, Szilvia Bősze, Gergő Gyulai, Mayra Quemé-Peña, András Wacha, Bálint Jezsó, Tamás Beke-Somfai
P1087 Novel peptide inhibito of SARS-CoV-2 infection
Nina Raasch, Lucas Weißenborn, Elie Richel, Olena Denysenko, Simon Schäfer, Heinrich Sticht, Klaus Überla, Jutta Eichler
P1088 Investigating protein prenylation using cell-permeable peptides
Martin Matijass, Merlin Klußmann, Annika Klimpel Ines Neundorf
P1090 Cytotoxicity and phototoxicity effects of modified temporin analogs with unnatural aminoacids
Tsvetelina Foteva, Ivan Iliev, Rositsa Hristova, Dilyana Dimitrova, Veronica Nemska, Nelly Georgieva, Dancho Danalev
P1092 Triazole-bridged peptides with enhanced antimicrobial activity and potency against pathogenic bacteria
Joshua Grabeck, Jacob Mayer, Axel Mayer, Michele Casoria, Michael Quagliata, Denise Meinberger, Andreas R. Klatt, Isabelle Wielert, Berenike Maier, Anna Maria Papini, Ines Neundorf
P1094 Rational design of a miniprotein to inhibit the oncogenic transcription factor MYC
B. Ellenbroek, J. Kahler, D. Arella, C. Lin, W. Jespers, S. Pomplun
P1095 Novel, non-covalent peptide furin inhibitors suppressing Zika virus replication
Aleksandra Helbik-Maciejewska, Gabriela Brzuska, Dawid Dębowski, Agata Gitlin-Domagalska, Andrea Lipińska, Ewelina Król, Krzysztof Rolka
P1096 Molecular investigation on peptide regulated Mfn 1 and Sirt 1 protein interactions in mitochondrial dynamics
Mahesh Kumar Cinthakunta Sridhar, Nir Qvit
P1098 The role of β-hairpins in aggregation of β-amyloid derived peptides
Elisabetta Galluppo, Claudia Honisch, Stefano Tartaggia, Mauro Carraro, Paolo Ruzza
P1099 Biological Evaluation of New Fell Analogues as Potential PDE4 Inhibitors
Veronica Nemska, Boryana Borisova, Marie Cochard, Stéphane Gérard, Dancho Danalev
P1100 Investigation of the role of Mfn2 and Drp1 protein-protein interactions in mitochondrial dynamics and its biological implications in cardiovascular diseases
Berhe Hayelom, Qvit Nir
P1101 Peptide and Probe: A two-pronged approach to investigating menaquinone binding peptides
Eilidh J. Matheson, Roy A. M. van Beekveld, Sarah Gothard, Paolo Innocenti, Nathaniel I. Martin, Markus Weingarth, Stephen A. Cochrane
P1104 A series of novel, selective matriptase inhibitors
Dębowski Dawid, Aleksandra Helbik -Maciejewska, Agata Gitlin-Domagalska, Malihe Hassanzadeh, Antoine Désilets, Pierre-Luc Boudreault, Richard Leduc, Anna Łęgowska, Krzysztof Rolka
P1105 Total synthesis and semi-synthesis of fluorinated analogues of the antifungal cyclic lipopeptide iturin A
Periklis Karamanis, Matthew Kiernan, Jimmy Muldoon, Paul Evans, Cormac D. Murphy, Marina Rubini
P1106 Design and antimicrobial activity of short and novel peptides
Ilaria Di Stefano, Silvia Rizzo, Dario Corbisiero, Francesca Bonvicini, Giovanna Angela Gentilomi, Walter Cabri, Tainah Dorina Marforio, Lucia Ferrazzano, Alessandra Tolomelli
P1109 Short Analogues Of Cathelicidins Pmap-36 And Bmap-27: Structure-Activity Relationship And Stability To Proteolysis
C. Peggion, A. Schivo, F. Albini, A. Di Stasi, B. Biondi, M. Mardirossian
P1110 HBP-5: A Leading Heparin-Binding Peptide with Remarkable Activity against Gram-negative Bacteria
Roberto Bello Madruga, Daniel Sandín, Javier Valle, David Andreu, Marc Torrent
P1112 Inhibitory activity and proteolytic stability in human serum of peptide inhibitors of the Vascular Endothelial Growth Factor A165/Neuropilin-1 complex
Dagmara Tymecka, Patrycja Redkiewicz, Piotr F.J. Lipinski, Aleksandra Misicka
P1113 Unlocking the Potential of Conotoxins: Chemical Synthesis Strategies and Biological Activity
Yazid Souf, Nicolas Inguimbert, Sebastien Dutertre
P1114 Mucroporin-M1 analogues: synthesis, conformation and structure-activity correlation
Claudia Storti, C. Peggion
P1115 Ferrocene-peptide conjugates with potential antitumor activity
Barbara Biondi, Beatrice Calderaro, Annalisa Bisello, Roberta Cardena, Renato Schiesari, Saverio Santi
P1116 Fragments of fibroblast growth factors useful in regenerative medicine components
Katarzyna Czerczak-Kwiatkowska, Adrianna Wierzbicka, Dorota Bociaga, Justyna Fraczyk, Beata Kolesinska
P1117 CR22DK-S18G Breakthrough: Revealing a novel antimicrobial peptide with rifampicin and isoniazid-like potency against Mycobacterium tuberculosis - a comprehensive exploration from synthesis to immune modulation and selective action
Cesar Augusto Roque-Borda, Laura Maria Duran Gleriani Primo, Rafaela Melo Pogianeli, Lucas Henrique Domingos da Silva, Isabela Caroline dos Santos, Flávia Aparecida Resende, Henrik Franzyk, Paul Robert Hansen, Fernando Rogério Pavan
P1119 In silico identification and chemical remodelling of tick protein epitopes for vaccine antigen development
Stepan S. Denisov, M. Amine Jmel, Wouter Peeters, Maya Idema, Michalis Kotsyfakis, Johannes H. Ippel, Tilman M. Hackeng, Ingrid Dijkgraaf
P1121 Harnessing GPCRs Biased Signaling: Novel Macrocyclic Analogs for Enhanced Cardiovascular Treatment with Reduced Side Effects
Kien Tran, Xavier Sainsily, Jérôme Côté, David Coquerel, Pierre Couvineau, Sabrina Saibi, Lounès Haroune, Élie Besserer-Offroy, Alexandre Murza, Jean-Michel Longpré, Mannix Auger-Messier, Michel Bouvier, Philippe Sarret, Pierre-Luc Boudreault
P1122 A Novel Regulation Method of mRNA by Recruiting Regnase-1 Using Binding Motif-Antisense Oligonucleotide Conjugates
Masayuki Fujii
P1124 Deoxythymidine-based antimicrobial peptidomimetics to combat drug-resistance
Eun Young Kim, Dinesh Kumar, Sung Tae Yang, Song Yub Shin
P1125 Fine-Tuning the Immune-Stimulatory and Cancer Cell Binding Properties of Immune System Engagers (ISErs)
Hannah Back, Manuel Felkl, Susanne Kremer, Claudia Altdorf, Ute Steinbusch, Christian FW Becker
P1126 Targeted Acidosis Mediated Delivery of Antigenic MHC-Binding Peptides
Joey J. Kelly, Emily T. Ankrom, Sarah E. Newkirk, Damien Thévenin, Marcos M. Pires
P1128 Hybrid synthetic approach and biological characterization of a branched heterodimer for overcoming prostate cancer heterogeneity
Santo Previti, Sacha Bodin, Emmanuelle Rémond, Clément Morgat, Florine Cavelier
P1129 Epitope-directed peptide screening and machine learning for HER2-targeted antibody-mimetic peptides
Tetsuya Kadonosono, Yutaka Saito
P1130 Enhancing the Gastrointestinal Stability of Salmon Calcitonin thought Peptide Stapling
Hiba Ghareeb, Norman Metanis
P1131 Development and Antifungal Efficacy of Hydrocarbon-Stapled Peptide Analogs Based on Human Antimicrobial Peptides for Candidiasis Therapy
Hyosuk Yun, Ganbaatar Byambasuren, Chul Won Lee
P1132 Prevention of the Spread of Virus Infection in Global Societies: Anti-SARS-CoV-2 Agents Learned from HIV Researches
Hirokazu Tamamura, Nobuyo Higashi-Kuwata, Hiroaki Mitsuya, Kohei Tsuji, Takahiro Ishii, Takuya Kobayakawa
P1133 Bicycle Radionuclide Conjugates (BRCs) as agents for tumour targeting
Anusha Regupathy, Ben Blakeman, Luca Mascheroni, Simone Pellegrino, Johanna Lahdenranta, Lisa-Charlotte Domogalla, Malgorzata Sulewska, Matthias Eder, Ann-Christin Eder, Gemma Mudd
P1134 Development of gut-restricted antibiofilm peptides to target gastrointestinal biofilms
B. Jandl, M. Lang, A. Makristathis, C. Gasche, M. Muttenthaler
P1135 Development of peptide modulators targeting proteinprotein interactions of the Sodium Leak Channel Complex
Emma Beyer, Stephan Pless
P1136 Application of membrane-active peptide-based therapeutics in the management of stromal melts associated with microbial keratitis
Jyoti Sood, Sujithra Shankar, Sushmita G. Shah, Shikha Yadav, Archana Chugh
P1137 One-bead-one-compound combinatorial libraries for the discovery of ligands towards SIRPα and checkpoint CD47 proteins
P. Quesada-Martínez, M. Sánchez-Navarro
P1138 Impaired metabolic phenotyping in mice with deletions of GPR10 and NPFFR2 receptors: Implications for lipidized PrRP analog therapy in obesity
Veronika Strnadová, Magdalena Škrlová, Jaroslav Kuneš, Lenka Maletínská
P1139 Latarcins as membrane active peptides for therapeutic applications
Sivalingam Ayyanar, Prasanjeet Kaur, Deepthi Poornima Budagavi, Nisha Ponnappan, Archana Chugh
P1140 Intranasal effects of an analogue of the gliopeptide ODN on energy homeostasis
Omayma Dlimi, Karthi Duraisamy, Arnaud Arabo, Léa Killman, Marie Jean-Claude Do Rego, Marie Jean-Luc Do Rego, Benjamin Lefranc, Amine Bourzam, Nicolas Chartrel, Jérôme Leprince
P1142 Enhancing biomedical metal implants with synthetic peptides: improved bioactivity and in vitro safety
Adrien Mourgot, Farzin Arjmand, Olivier Monasson, Michel Boissiere, Madjid Djemai, Souad Ammar-Merah, Guy Dirras, Elisa Peroni
P1143 StreaMLine - Machine learning guided development of novel GLP-1 receptor agonists
Claudia Hjørringgaard, Jens Christian Nielsen, Mads Mørup Nygaard, Anita Wester, Lisbeth Elster, Trine Porsgaard, Randi Bonke Mikkelsen, Silas Rasmussen, Andreas Nygaard Madsen, Morten Schlein, Niels Vrang, K. Rigbolt, Louise S. Dalbøge
P1144 Development of a HPMC-patch containing RGD and KTTKS peptide sequences for application in tissue healing
Naiara Maia Pereira, Reinaldo Marchetto
P1146 Optimisation of a TREM2 receptor inhibitor peptide
Claudia Honisch, M. Rotondo, E. Galluppo, S. Tartaggia, C. Gallo, M. Dell’Isola, D. Carbone, E. Manzo, A. Fontana, P. Ruzza
P1149 Synthesis and Characterization of Tumor Targeted Peptide (TTP) Conjugated with Magnetic Nanoparticles for Thermo-ablation
Sima Alvani Alamdari, Justyna Fraczyk, Joanna Waśko, Anita Plazinska, Beata Kolesinska
P1150 Synthesis and characterization of phenethyl isothiocyanate conjugated with magnetic nanoparticles modified by tumor targeting peptide (TTP) using in cancer treatment
Sima Alvani Alamdari, Łukasz Janczewski, Justyna Fraczyk
P1151 Analysis of Mannan (polymannose) Conjugated with 35-55 Immunodominant Epitope of Myelin Oligodendrocyte Glycoprotein for the Treatment of Multiple Sclerosis
Carmen Simal, Areti Gkika, Maria-Eleni Androutsou, Georgia Biniari, Alexios Aletras, Theodore Tselios
P1152 A Nanomolar Potency Macrocyclic Peptide Inhibitor of SARS-CoV-2 Spike through Deep Mutational Scanning
Antonius J.P. Hopstaken, Oliver J. Debski-Antoniak, Preeti Hooda, Daniel L. Hurdiss, Seino A.K. Jongkees
P1153 Intelligent wound dressing with antimicrobial properties
Sebastian Kersting, Sophia Ohnesorg, Markus von Nickisch-Rosenegk
P1154 High Throughput Phage Display Screening Identified Peptide Inhibitors Targeting the α-Synuclein for Parkinson’s Disease Treatment
Haiyan Zhou, Zhaohui Liang, Chenyin Wang, Wai Lok Ngai, Michael K. Chan, Chaogu Zheng, Xuechen Li
P1155 Linear peptides as IgG-epitope mimetic for allergic immunotherapy against birch pollen
Alessandro Streuli, Lara Šošić, Marta Paolucci, Agathe Duda, Klaus Eyer, Pål Johansen, Christian Steuer
P1160 Discovery of a novel α-helical peptide targeting GTP-bound K-Ras(G12D)
Hannah Comfort, Sarah Ross, Jefferson Revell, Thomas Murray, Carole Urbach, Bethan Archer, Darerca Owen, Helen Mott
P1161 Peptide Inhibitors of Protein-Protein Interactions Targeted to Src Homology 2 Domains: A Combined Computational and Spectroscopic Design Approach
Paolo Calligari, Claudia Storti, Chiara Innamorati, Chiara Fulci, Alessia Damiani, Cristiano DI Stefano, Chiara Cocca, Cristina Peggion, Barbara Biondi, Gianfranco Bocchinfuso, Lorenzo Stella
P1162 Peptide-based vesicle isolation method for P. aeruginosa
Tania Henriquez, Ismael Castañón, Silvia Scali, Chiara Falciani
P1164 Antibacterial, Anti-inflammatory and Anti-biofilm Activities of Novel Short Antimicrobial Peptides Designed from the Cecropin A-Melittin Hybrid Antimicrobial Peptide, BP100
Eun Young Kim, Dinesh Kumar, Sang Hyun Park, Song Yub Shin
P1165 Study on the stability of new promising antimicrobial peptides against protease activities present in infection sites
Clelia Cortese, Giovanni Cappello, Laura Cresti, Virginia Niccolini, Marco Scocchi, Marialuisa Mangoni, Alessandro Pini
P1170 Revolutionizing Peptide Production: Introducing An Engineered TEV Protease
R. Guerrette, C. Schwarz, B. Wetzel
P1172 Spatio-temporal control of cellular differentiation for cartilage tissue engineering
Jules Simonin Garcia, Cécile Echalier, Emmanuel Belamie, Marie Morille, Gilles Subra
P1173 Development of a novel alternative method for liraglutide production
Gabriela R. Barredo-Vacchelli, Jésica A. Rodríguez, Joaquín A. Eloy, Silvia A. Camperi
P1174 Comparison of in vitro immunogenicity between δ-ctenitoxin-Pn2a and epitope-based immunogens
Jésica A. Rodríguez, Gabriela R. Barredo-Vacchelli, Ariadna M. Birocco, Agustín Blachman, Gerardo Acosta, Fernando Albericio, Graciela C. Calabrese, Silvia A. Camperi
P1176 Extracellular-Vesicle Catch-and-Release isolation System using a Net-charge Invertible Curvature-sensing peptide
Kenichi Kawano, Yuki Kuzuma, Koichi Yoshio, Kenta Hosokawa, Yuuto Oosugi, Takahiro Fujiwara, Fumiaki Yokoyama, Katsumi Matsuzaki
P1178 Multifunctional peptides for the synthesis of photothermally active gold nanoparticles
Alžbeta Runová, Helma Wennemers
P1179 Intracellular Peptide Library Screening for Covalent Transcription Factor Inhibitors
Andrew Brennan, Keith Vance, Scott Lovell, Jody Mason
P1182 Innovative microfluidic preparation of monodisperse peptidic nanoparticlesfor ultrasound guided gene delivery
Guy Gouarin, Vicentiu Moraru, Samir Cherkaoui
P1186 Environment Responsive Peptide Dimers Bind and Stabilize dsRNA
Niall M. McLoughlin, Marvin A. Albers, Estel Collado Camps, Jannik Paulus, Youri A. Ran, Saskia Neubacher, Sven Henning, Roland Brock, Tom N. Grossmann
P1187 Engineered oxalyl thioester-containing protein domains as a building block for synthetic biopolymers
Francesco Terzani, Simindokht Rostami, Chen Wang, Benoît Snella, Birgit Wiltschi, Oleg Melnyk, Vangelis Agouridas
P1188 Improved Sortase A-Catalyzed Transpeptidation by Selective Electrostatic-Assisted Aminolysis Trapping
Chen Wang, Benoît Snella, Rémi Desmet, Oleg Melnyk, Vangelis Agouridas
P1189 Photocontrollable probes for the investigation of neuropeptide signalling
Konstantin Raabe, Predrag Kalaba, Hilary Yong, Erik Keimpema, Victor Anggono, Markus Muttenthaler
P1191 Bind&Bite: Covalently stabilized heterodimeric coiled-coil peptides for the site-selective chemical modification of proteins
Jannis Beutel, Riccardo di Vincenzo, Klaus Überla, Jutta Eichler
P1194 Protein Interface Catalysed Capture (PICC) to Resolve the Structure of the Tau-PSD95 Protein Complex
Reuben Blades, Kanishka Pushpitha, Gene Hart-Smith, Muhammad Bin Zenaidee, Daryl Ariawan, Lars Ittner, Ole Tietz
P1195 In vitro selection of highly N-alkylated cyclic peptides for targeting intracellular protein-protein interactions
Takeo Iida, Atsushi Ohta, Yusuke Yamagishi, Tetsuo Kojima, Hitoshi Iikura
P1200 Study on the Role of Helix-Stabilized Peptides in Transporting Antisense Morpholino Oligomers into Cells: Relationships among Helicity, Cellular Uptake, and Antisense Activity
Hiroyuki Takada, Keisuke Tsuchiya, Yosuke Demizu
P1203 Synthesis of Bacteria-Derived Lipopeptides and Applications in Antibiotic Discovery
Glenna Swinand, Katherine Bowen, Samir Olatunji, Martin Caffrey, Eoin M. Scanlan
P1204 Controlled Intracellular Trafficking and Gene Silencing by Oligonucleotide-Signal Peptide Conjugates
Masayuki Fujii
P1205 Polysaccharides modified with attenuated cationic lytic peptides: Formation of microparticles and their use in cytosolic antibody delivery
Junya Michibata, Yoshihiro Sasaki, Kazunari Akiyoshi, Shiroh Futaki
P1206 Probing the interplay between Ubiquitination and Adenosine-Di-Phosphate ribosylation
Max S. Kloet, Jim Voorneveld, Qiang Liu, Robbert Q. Kim, Ivan Ðikić, Huib Ovaa, Dmitri V. Filippov, Gerbrand J. van der Heden van Noort
P1207 Virucidal Peptide-Based Drugs to Target Influenza
Shadi Kordbacheh, Francesca Olgiati, Francesco Stellacci
P1210 Linkerology of Cryptophycin Drug Conjugates
Jan-Niklas Bollnow, Cedric Dessin, Norbert Sewald
P1211 The series of a new fluconazole-based conjugates with cell penetrating and antimicrobial peptides
Natalia Ptaszyńska, Daria Łada, Wioletta Brankiewicz, Katarzyna Serbakowska, Jan Lica, Marek Drab, Natalia Maciejewska, Anna Łęgowska, Piotr Szweda, Krzysztof Rolka
P1212 Click-to-Release-based Cryptophycin Drug Conjugates
Jona Voss, Peter Bitsch, Cedric Dessin, Harald Kolmar, Norbert Sewald
P1213 Strategies for designing hepatocyte-selective carriers using helical peptides as stable scaffolds
Takahito Ito, Takashi Misawa, Nobumichi Ohoka, Michihiko Aoyama, Takao Inoue, Akiko Ishii-Watabe, Yosuke Demizu
P1214 Synthesis and characterization of bioconjugates containing peptide moiety with potential anticancer activity
Dancho Danalev, Polya Miladinova, Yordan Todorov, Ivan Iliev
P1216 Rational design, synthesis and evaluation of mitoxantrone conjugated with mutated Gonadotropin Releasing Hormone (GnRH) for the treatment of hormone-dependent cancer
Georgia Biniari, Agathi Nteli, Christos Markatos, Vlasios Karageorgos, Alexios Vlamis-Gardikas, George Liapakis, Maria Venihaki, Theodore Tselios, Carmen Simal
P1217 New peptide-porphyrin conjugates targeting brain-residing viruses
Toni Todorovski, Giuseppina Guida, Patrizia Janković, Diogo Mendonça, Christine Cruz-Oliveira, Marco Cavaco, Daniela Kalafatović, Sira Defaus, Andrea Da Poian, Miguel Castanho, David Andreu
P1218 Development of Daunomycin-Peptide Antitumor Conjugates Containing Neurotensin-Based Homing Moiety
Levente E. Dókus, Eszter Lajkó, Orsolya Láng, László Kőhidai, Gábor Mező
P1220 Peptide fibrils as nanocarrier for targeted therapy
Justyna Sawicka, Milena Czeszejko, Ewa Wieczerzak, Paweł Niedziałkowski, Tomasz Kulesza, Kamila Kitkowska, Rafał Sądej, Sylwia Rodziewicz-Motowidło
P1221 De novo Semi-synthetic Platform for Monitoring Protein degradation in Live Cells
Mahdi Hasan, Deepanjan Panda, Guy Mann, Ashraf Brik
P1223 Design of aptamer conjugates as monoclonal antibody mimics
Jordan Cossu, Océane Ricloux, Corinne Ravelet, Véronique Frachet, Eric Peyrin, Didier Boturyn
P1224 Conjugates containing homing peptide, cell penetrating peptide and a cytostatic or marker potentially useful in the diagnosis or treatment of lung cancer diseases
Piotr Jedrzejczak, Anna Gajda, Justyna Fraczyk, Beata Kolesinska
P1225 Development of novel amphipathic stapled peptides as DDS carriers for intracellular delivery of nucleic acids
Motoharu Hirano, Hidetomo Yokoo, Makoto Oba, Takashi Misawa, Yosuke Demizu
P1227 Development of selective peptide-based radiopharmaceuticals for targeted therapy and diagnosis of high malignant cancers
Anna Giorgio, Nicola Salvarese, Annarita Del Gatto, Michele Saviano, Cristina Bolzati, Laura Zaccaro
P1228 Control of biological processes using metallopeptides
Jessica Rodriguez Villar
P1229 pH-Dependent Cellular Uptake of CPPs – Guanidinium versus OxyguanidiniumProline
Rahel Heeb, Laura Massaad, Helma Wennemers
P1230 Lipophilic Prodrug Charge Masking- insights into new method of peptide prodrugs synthesis conception
Agata Gitlin-Domagalska, Anna Olejnik, Natalia Ptaszyńska, Jaroslaw Ruczyński, Mladena Glavaš, Mikolaj Marszałek, Dawid Dębowski, Aleksandra Helbik-Maciejewska, Anna Łęgowska, Chaim Gilon, Krzysztof Rolka
P1231 Amphipathic Proline-Rich Cell Penetrating Peptides for Mitochondria Targeting
Adeline M. Schmitt, Helma Wennemers
P1233 Optimization of Anti-Vasoconstricting UT-II-Derived Biogels
Thibault Cauwenbergh, Juliana Dallagnol, David Chatenet, Charlotte Martin, Steven Ballet
P1234 Development of cell penetrating peptide-based ubiquitin ligase ligand for the development of PROTAC
Hidetomo Yokoo, Zhou Dongrui, Yosuke Demizu
P1236 Design and characterization of CD20 antigen surfaces for the selection of rituximab peptide mimics
Océane Ricloux, Chanantida Jongwohan, Jordan Cossu, Liliane Guerente, Didier Boturyn
P1240 Development of Novel Angiopep-2 Conjugates for Cancer Treatment
Gábor Mező, Levente Dókus, Diána Vári-Mező, Krisztina Kiss, Lilla Pethő, Ivan Ranđelović, József Tóvári, Szilvia Bősze
P1241 Systematic Determination of the Effects of Macrocyclization on Peptide Permeability into Mycobacteria
Rachita Dash, Irene Lepori, Han Zhang, Wonpil Im, M. Sloan Siegrist, Marcos M. Pires
P1242 Lipophilic Prodrug Charge masking strategy for novel oxytocin prodrugs production
Agata Gitlin-Domagalska, Natalia Ptaszyńska, Anna Olejnik, Jaroslaw Ruczyński, Mladena Glavaš, Dawid Dębowski, Aleksandra Helbik-Maciejewska, Anna Łęgowska, Chaim Gilon, Krzysztof Rolka
P1243 Drug-likeness of cyclic peptides beyond Rule of 5
Shojiro Shinohara, Mikimasa Tanada, Yuya Morita, Kazuhiko Nakano, Takuya Shiraishi, Hitoshi Iikura
P1244 POM-peptide hybrid against Alzheimer's Desease
Marta Giacomini, Claudia Honisch, Elisabetta Galluppo, Genny Orso, Haihong Yu, Mauro Carraro, Paolo Ruzza
P1245 The potential use of peptides in pancreatic cancer
Martina Rotondo, Giovanna Bossio, Sofia Parassia, Andrea Mattarei, Claudia Honisch, Ildikò Szabò, Lucia Biasutto, Paolo Ruzza
P1246 Evaluation of different spin labels for the study of protein-peptide interaction in cellular extract using Electron Paramagnetic Resonance spectroscopy techniques
Claudia Toso, Giovanni Loprete, Elisabetta Bergantino, Simone Fabbian, Massimo Bellanda, Sylvain Marque, Gerard Audran, Marina Gobbo, Marta De Zotti, Donatella Carbonera, Marco Bortolus, Marilena DI Valentin
P1247 Development of a cell penetrating peptide carrying a biological active HPV16 E6 inhibitory molecule for delivery into cervical cancer cells
Anna Lucia Tornesello, Luisa Dassi, Vincenza De Gregorio, Giorgia Imparato, Marilisa Leone, Lu Wuyuan, Noemy Starita, Andrea Cerasuolo, Luigi Buonaguro, FrancoMaria Buonaguro, Maria Lina Tornesello
P1249 The Antimicrobial Peptide SET-M33: In Vivo Efficacy and Toxicity in Different Animal Species and Encapsulation in Inhalable Polymeric Nanoparticles for Pulmonary Delivery
Laura Cresti, Giovanni Cappello, Clelia Cortese, Virginia Niccolini, Alessandro Pini
P1250 Affibody-mediated peptide nucleic acid pretargeting for delivery of cytotoxic payloads to HER2 positive carcinoma
Jacob Clinton, Kristina Westerlund, Amelie Eriksson Karlström
P1251 Structure-activity relationship study on the P4 structure of macrocyclic BACE1 inhibitors
Kazuya Kobayashi, Momoka Kawakita, Takuya Otani, Yasaunao Hattori, Shinya Oishi
P1253 Non-Enzymatic Protein Catalyses Amide Bond Formation
Nicolas Brauckhoff, Laura Fang, Anissa Haim, Tom N. Grossmann
P1254 β-Sheet mimetics that Target the Transcriptional Coactivator β-Catenin
M. Wendt, A. Yeste-Vázquez, T. van Ramshorst, R. J. Hana, N. M. Pearce, S. Hennig, T. N. Grossmann
P1255 Solid-phase synthesis of peptoids with structure-inducing tert-butyl side chains: A unique challenge finally met
Zacharie Bordas, Sophie Faure, Olivier Roy, Claude Taillefumier
P1256 Combinatorial solid phase peptide synthesis of peptides on glass slides and thermographic investigation on CO2 -binding affinity
Jessica Jung-Fittkau, Katharina Moro, Josef Diebold, Andrea Kruse, Hans-Peter Deigner, Magnus Schmidt
P1257 Stabilization of a miniprotein fold by an unpuckered proline surrogate
Madison M. Wright, Benjamin H. Rajewski, Taylor A. Gerrein, Lorna J. Smith, W. Seth Horne, Juan R. Del Valle
P1259 Exploring the potential of CXCR4 mimetic peptides to target cancer cells
Showmika Srirangan, Chafia Chiheb, Sebastian Stäbler, Anja Bosserhoff, Jutta Eichler
P1260 The ornithine-based siderophore as a potential carrier of peptide nucleic acid into Escherichia coli
Uladzislava Tsylents, Michał Burmistrz, Piotr Maj, Monika Wojciechowska, Joanna Trylska
P1261 Stepwise chemical control in the formation of beta-peptide assemblies
Imola Cs. Szigyártó, Kristóf Ferentzi, Kamal el Battioui, Olivér Pavela, András Wacha, Viktor Farkas, Tamás Beke-Somfai
P1262 Low-Molecular α-Amino Acid-Based Derivatives as Nanocarriers of Plant Growth Regulators
Vasilena Kondova, Borislav Anchev, Konstantin Dochev, Daniela S. Tsekova, Mariana Sichanova, Maria Geneva
P1264 From Peptides to Bioactive Lactam-constrained Foldamers
Maxime Fillaudeau, Alexandre Messerschmitt, Arie Van der Lee, Lubomir Vezenkov, Luc Brunel, Young Kee Kang, Jean Martinez, Baptiste Legrand, Muriel Amblard
P1265 Development of Neurotensin(8-13) Analogs as Potent NTS1/NTS2 Receptor Ligands with Enhanced Effects on a Mouse Model of Parkinson’s Disease
Nikolay T. Tzvetkov, Toni Kühl, Maya G. Georgieva, Harald Hübner, Maria Lazarova, Polina Petkova-Kirova, Tamara I. Pajpanova, Reni Kalfin, Lyubka Tancheva, Aneliya A. Balacheva, Peter Gmeiner, Diana Imhof
P1266 Synthesis and biological application of a short peptidomimetics based on bacterial cell wall peptidoglycan monomer
Marcela Šišić, Leo Frkanec, Ruža Frkanec
P1267 Antimicrobial peptidomimetics against methycillin-resistant Staphylococcus aureus (MRSA)
Katarzyna Łada, Maria Dzierżyńska, Agnieszka Gajewicz-Skrętna, Łukasz Grabowski, Alicja Węgrzyn, Franciszek Kasprzykowski, Sylwia Rodziewicz-Motowidło
P1268 Synthesis of 5-member heteroaromatics containing peptide backbone: pro and cons of structural constrains induced by amide bond surrogates
Francesco Brenzini Biagioni, Corentin Layec, Karine Porte, Pierre-Yves Renard, Anna Maria Papini
P1270 PepFuNN: Novo Nordisk open-source toolkit to enable peptide in silico analysis
Rodrigo Ochoa, Kristine Deibler
P1271 A peptide database from human feces to foster the discovery of novel bioactive peptides
Armando A. Rodriguez, Nico Preising, Merve Karacan, Thomas Seufferlein, Martin Wagner, Frank Kirchhoff, Jan Münch,Ludger Ständker, Sebastian Wiese
P1272 Application of the MALDI-MS and MALDI-IMS in the identification of the GPR146 receptor in tissue preparations
Joanna Waśko, Aleksandra Ryk, Wojciech Fendler, Beata Kolesińska
P1273 Searching for biomarkers characteristic for severe stage of COVID-19
Aleksandra Czerchawy, Joanna Waśko, Beata Kolesińska
P1274 Identification of Delftia lacustris Proteins in Response to Cadmium Stress.
Ximena Carolina Pulido Villamil, Jefferson Beltrán, Maryeimy Varón-López, Cesar Augusto Jaramillo
P1275 Proteins Involved in the Plant Growth Promotion of Pseudomonas orientalis in the Presence of Cadmium
Ximena Carolina Pulido Villamil, Jefferson Beltrán, Maryeimy Varón López, Cesar Augusto Jaramillo
P1276 Identification of protease inhibitors from the human peptidome to develop novel antivirals
Armando A. Rodríguez, Jan Lawrenz, Nico Preising, Merve Karacan, Bernd Schröppel, Rene van Erp, Eberhard Barth, Marion Schneider, Ludger Ständker, Frank Kirchhoff, Jan Münch, Sebastian Wiese
P1277 An Advanced Database for GlycoPeptide Structure Exploration to build GlycoPeptideStructure Hub: GPS Hub
Michele Casoria, Marina Macchiagodena, Carla Bazzicalupi, Claudia Andreini, Gianni Cardini, Anna Maria Papini, Marco Pagliai
P1278 Machine Learning Reveals Structural Properties of Monosaccharides and their Peptide Conjugates
Michele Casoria, Marina Macchiagodena, Carla Bazzicalupi, Claudia Andreini, Gianni Cardini, Anna Maria Papini, Marco Pagliai
P1279 Mechanistic basis for the role of acidic tail of Rad6 (ubiquitin-conjugating enzyme) in Bre1 (E3 ligase) mediated recognition of histones in Saccharomyces cerevisiae
Pawan Yadav, Manish Gupta, Mohan Kamthan, Pankaj Kumar
P1280 Arginine-rich peptides vs. lysine-rich peptides: interaction with differently charged lipid bilayers
Andreja Jakas, Lea Pašalić, Danijela Bakarić
P1283 Prediction and simulation of the S100A1ct peptide with a membrane environment
Tommaso Bartoloni, Manuel Glaser, Julia Ritterhof, Patrick Most, Rebecca Wade
P1285 Engineering Stable Miniproteins: The Journey from Computational Design to Tertiary Structure Stability
Natalia Miodowska, Ewa Rudzińska-Szostak, Vitaly Kovalenko, Łukasz Berlicki
P1286 Enhancing computational peptide therapeutic design with quantum chemistry and quantum computing
Vikram K. Mulligan, Tristan Zaborniak, P. Douglas Renfrew, Benjamin Brown
P1287 Formation of native disulfide bond patterns in small antifungal proteins and their gamma-core optimized analogs
Györgyi Váradi, László Galgóczy, András Czajlik, Attila Borics, Gábor Bende, Csaba Papp, Zoltán Kele, Gyula Batta, Gábor K. Tóth
P1290 Alanine scanning analysis of the antimicrobial peptide lyp1987 using a template-based approach
Jomari Fernando, Jeremiah Batucan, Jacquelyn Peran, Lilibeth Salvador-Reyes, Aaron Joseph Villaraza
P1292 Synthesis and assessment of amyloidogenic activity of the C-peptide fragments
Joanna Waśko, Beata Kolesińska
P1293 High-Throughput Synchrotron Radiation Circular Dichroism (HT-SRCD) for the screening of G-quadruplex ligands
Martina Rotondo, Claudia Honisch, Barbara Biondi, Pietro Spanu, Fausta Ulgheri, Giovanni Loriga, Andrea Beccu, Rohanah Hussain, Giuliano Siligardi, Paolo Ruzza
P1295 Design and Synthesis of a Diamino Diacid-based Short Cyclic Peptide with Tunable Self-Assembly
Devki Nandan, Ramesh Ramapanicker
P1296 Effect of lipid peroxidation on protein conformational stability
Claudia Honisch, M. Rotondo, S. Tartaggia, R. Hussain, G. Siligardi, P. Ruzza
P1297 Three-dimensional structure and membrane permeability relationship of cyclopropane-restricted cyclic peptides
Yuki Yamazaki, Hiroyuki Kumeta, Satoshi Shuto, Mizuki Watanabe
P1298 Methyl-based NMR methods for characterization of large peptide self-assemblies
Dörte Brandis, Fanny Kozak, Christian W. F. Becker, Dennis Kurzbach
P1299 Silaffin 1A1: Insights to the Processes of Tailored Silica Precipitation
Fanny Kozak, Fabian Daus, Dörte Brandis, Armin Geyer, ChristianW. F. Becker, Dennis Kurzbach
P1302 Rational design of polyfluorinated peptide-based materials: Self-assembly of an amphiphilic motif
Maurizio Iannuzzi, Suvrat Chowdhary, Holly Fiedler, Kilian Haoues, Boris Schade, Andreas F. Thünemann, Elisa Quaas, Beate Koksch
P1303 Let's do the Twist - Chiral Information Transfer in Supramolecular Peptide Complexes
Danielle Aria Liebnitz, Pernille Vosbein-Christensen, Andrew Thomson
P1306 Tailoring the self-assembly of cyclic peptide scaffolds for prostate cancer imaging
Fátima Santillán, Carlie Charron, Betty C. Galarreta, Leonard G. Luyt
P1307 Computational/Experimental Symbiosis in the Design of Supramolecular Peptide Architectures
Ivan R. Sasselli, Laura Perez-Chirinos, Aitziber L. Cortajarena, Zaida Alvarez
P1310 Ultrasound-assisted formation of therapeutic peptide microcapsules
Gabriele Rossi, Erica Belforte, Francesca Cavalieri, Ana Aguilera, Mariano Venanzi
P1311 Tailoring Peptide Self-Assembly with Electron Donor Functionalization Towards Formation of Vesicles, Helical Ribbons, and Fibers
Laura Brüchle, Thomas Heim, Milan Kivala, Franziska Thomas
P1312 Crosslink reaction of α-/ω-substituted diacrylate polyethylene-glycol in Fmoc-FF hydrogel matrices
Carlo Diaferia, Paolo Pellegrino, Giancarlo Morelli, Rosaria Rinaldi, Antonella Accardo
P1313 Innovative Strategies for Sustainable Materials: Developing Protein-Based Bioplastics from Rapeseed By-Products for a Circular Economy
Sara Aquilia, Michele Pinna, Anna Maria Papini, Francesco Ciardelli, Luca Rosi, Claudia Bello.
P1314 Self-assembled Peptides for Biomimetic Mineralization and Enamel Repair
Yue Li, Rong Chang, Yang-Jia Liu, Feng Chen, Yong-Xiang Chen
P1315 Cationic amphiphilic peptide-based delivery platforms for negatively charged active pharmaceutical ingredients including short interfering RNA
M. Rosa, C. Diaferia, A. Accardo, G. Morelli
P1316 Synthesis of peptidomimetics using Diaryl-β2,3 amino acids for the preparation of smart materials
Dulce A. Quintana-Romero, Raffaella Bucci, Merve Gul, Maria M. Pérez-Madrigal, Carlos Alemán, M. Luisa Gelmi
P1317 Conformational and self-assembly studies of a protein-mimetic peptide from Pseudomonas aeruginosa’s YeaZ protein
Elettra Fasola, Giulia Alboreggia, Stefano Pieraccini, Francesco Oliva, Fatima Ezzahra Agharbaoui, Michela Bollati, Giovanni Bertoni, Sandro Recchia, Marcello Marelli, Umberto Piarulli, Sara Pellegrino, Silvia Gazzola
P1318 A comparative study between phenylglycine- and phenylalanine-derived peptide hydrogels
Jolien Bertouille, Ulrich Hennecke, Charlotte Martin, Ana V. Cunha, Steven Ballet
P1319 Peptides stapling as a tool for improving molecular recognition of C-reactive protein
K. Szot-Karpińska, M. Lubos, N. Cwalina, J. Pícha, J. Kaminský, J. Jiráček, M. Majewska, M. Narajczyk, J. Niedziółka-Jönsson
P1320 A structural sight on peptides forming stable LLPS: a combined experimental and computational investigation
Gianfranco Bocchinfuso, Francesca Cavalieri, Daniel O. Cicero, Annachiara Ferrara, Hilda Garay-Perez, Greta Petrella, Marco Savioli, Mariano Venanzi
P1321 From Synthesis To Application: Peptide-Functionalized Nanoformulations For Biomedical Applications
Shubhi Joshi, Gaurav Verma, Avneet Saini
P1322 Sustainable Development of Cross-Linked Films from Rapeseed Meal
Sara Aquilia, Michele Pinna, Anna Maria Papini, Francesco Ciardelli, Luca Rosi, Claudia Bello
P2002 Suspension Bead Loading (SBL): An Economical Protein Delivery Platform to Study URM1’s Behavior in Live Cells
Reem Mousa, Abhishek Saha, Yam Alalouf, Pradeep Sadhu, Mahdi Hasan, Shaswati Mandal, Guy Mann, Ashraf Brik
P2003 Synthesis and Conformational Analysis of β,β-Diaryl-α-Amino Acids: on the Way to Molecular Gearing
Timo Zimmer, Armin Geyer
P2004 A green peptide synthesis protocol for improving peptide production: a new approach
Luana Lastella, Barbara Biondi, Ivan Guryanov, Fernando Formaggio, Marco Macis, Antonio Ricci
P2005 A Rapid and Efficient Photochemical Modification Strategy for Late-Stage Peptide and Protein Functionalization
Meng-Qian Zhang, Yan-Mei Li
P2008 Novel Selectively Cleavable Dmb-Based Protecting Groups for Side Chain Amino Groups of Amino Acids
Raimund Maier, Karin Rustler, Thomas Bruckdorfer, Udo Kalejs, Vilnis Liepins, Kai Holland-Nell, Jacqueline Dalski, Stephan Pritz
P2009 Conformational editing and intracellular delivery of intrinsically disordered protein domain
Alexis Jouin, Alastair McEwen, Pierre Poussin-Courmontagne, Bruno Kieffer, Vladimir Torbeev
P2010 Palladium-mediated S-arylation and S-allylation for late stage peptide functionalization and protein conjugation
Ross D. Ballantine, Mingxiang Zhu, Ameni Hadj Mohamed, Aromal Asokan, Linhuan Shen, Mélanie Chenon, Ana Novak, Vincent Robert, Séverine Morisset-Lopez, Massimiliano Beltramo, Carlo Pifferi, Vincent Aucagne, Samir Messaoudi
P2011 Total Chemical Synthesis of Nanobodies for Targeted Cancer Therapy
Keziah Poggenpoel, Kevin Beijerling, William Kelton, Jiwon Hong, Margaret A. Brimble, Iman Kavianinia
P2012 Green Synthesis of a Novel Primary Amine Protecting Group for Solid-phase Peptide Synthesis
Clouie Justin Aguilar, Makhdoom Sarwar, Margaret A. Brimble, Iman Kavianinia
P2013 New Opportunities for Side-Chain Functionalization of Halogenated Amino Acids
Laura Cerveson, Norbert Sewald
P2014 Sculpting cavities in alpha-helical bundles to accommodate ligands of different size and shapes
Katarzyna Ozga, Rokas Petrenas, Joel J. Chubb, Derek N. Woolfson
P2015 Efficient and glycoeconomic synthesis of densely clustered mucin glycopeptides
Arseniy Galashov, Ekaterina Kazakova, Oliver Seitz
P2017 Targeting LAT1 with technetium(I)-99m-labeled tryptophan derivatives for SPECT imaging
Rúben D.M. Silva, Cristina P. Matos, Catarina I.G. Pinto, Joana F. Guerreiro, Lurdes Gano, Filipa Mendes, João D.G. Correia
P2018 Applications of Thiol-ene and Thiol-yne Chemistry for Peptide Stapling and Bioconjugation
Inés Rabadán González, Joshua Mclean, Nikitas Ostrovitsa, Sheila Fitzgerald, Andrea Mezzeta, Lorenzo Guazzelli, Donal O'shea, Eoin M. Scanlan
P2019 Greening Peptide Purification Through Use of Elevated Temperatures
Colin Simpson, Drew Cesta, Sandeep Singh, Jonathan Collins
P2020 Enzymatic Peptide and Protein Bromination: The BromoTrp Tag
Nicolai Montua, Norbert Sewald
P2021 Combining quaternary ammonium compounds and peptides- its application to antimicrobials and beyond
Rolland Lin, Margaret A. Brimble, Brian H. Northrop, Alan J. Cameron
P2022 Fluorescent Amino Acids with large Stokes Shift
Nicolas Schnatmann, Norbert Sewald
P2023 Propargylamine Amino Acids as Constrained Nε-Substituted Lysine Mimetics
Kevin Van holsbeeck, Mathias Elsocht, Steven Ballet
P2024 Synthesis and Structural Characterization of Trifluoromethylated Tetrahydroisoquinolines as New Constrained Aromatic Amino Acid Surrogates
Lilian Loisons, Steven Ballet, Thierry Brigaud, Simon Gonzalez
P2025 Cysteine Thioaldehydes : Photolytic Generation and Reactivity
Ardra Karthika, Matthew Murray, Guillermo Palop, Lee-Ann Keane, Patrick McArdle, Luke Crehan, Nicholas Yates, Alison Parkin, Martin Fascione, Eddie L. Myers
P2026 Application of a new green protocol in Solid-Phase Peptide Synthesis: identification of a new green solvent mixture compatible with ETT/TBEC
G. Vivenzio, M. Scala, P. Campiglia, M. Sala
P2029 Modular Access to Structurally Defined Ubiquitin Chains
Moritz Urschbach, Susanne Huhmann, Luca Ferrari, Dominik Vogl, Dominik Appel, Sascha Martens, Christian F. W. Becker
P2034 Tetrahydropyranyl and Tetrahydrofuranyl as New Backbone Protecting Groups For Enhanced Fmoc SPPS
Samuel J. Paravizzini, Craig A. Hutton, John A. Karas
P2035 Exploring Innovative Liquid-Phase Peptide Synthesis Strategies with Silane-Containing Molecules
Naoki Nishizawa, Akihiro Nagaya, Shota Murase, Yuji Mimori, Michiharu Handa, Ayumu Matsuda, Yutaka Kobayashi, Haruaki Kurasaki, Douglas R. Cary, Keiichi Masuya
P2037 Influence of tryptophan insertion on the fibrillation capacity and antimicrobial efficacy of β-Hairpin Antimicrobial Peptides
Dhanya Mahalakshmi Murali, Jian Xu, Dai Thien Nhan Tram, Pui Lai Rachel Ee
P2040 Cyclic Antimicrobial Peptides Guanidino-based Analogues of Temporin L
I. Boccino, R. Bellavita, M.R. Loffredo, F. Cappiello, B. Casciaro, M.L. Mangoni, P. Grieco, F. Merlino
P2041 From clotting to calcification: Gla-domains as guardians of vascular remodeling
S.M. Agten, A. Gentier, D.P.L. Suylen, S. Peijenborgh, M. Hochstenbach, L.J. Schurgers, T.M. Hackeng
P2042 Design and Synthesis of Peptide Modulators of Gαi/s Proteins
Anna Pepanian, Sabriye Aydoğdu, F. Ayberk Binbay, Pradipta Ghosh, Dehua Pei, Diana Imhof
P2045 Synthesis of Macrocyclic Thiolactone Peptides via Radical Acyl Thiol-Ene
Alby Benny, Eoin M. Scanlan
P2046 Divalent metal ions-directed release of C-terminally modified peptides at 60 °C under mild conditions
Rebeca G. Moura, Thiago de Souza Freire, M. Terêsa Machini
P2047 Exploring the Three-Dimensional Structures and Activity Relationships of N-Methyl and N-Desmethyl Analogues of Cyclodepsipeptide Destruxin E
Takayuki Doi, Hiroshi Sato, Hiroshi Nakagawa, Masahito Yoshida
P2048 Green solvents and Safe Reagents in SPPS taking advantage of induction heating and automation: synthesis and HPLC-free purification of difficult sequences
L. Pacini, M. Muthyala, O. Marder, L. Aguiar, R. Zitterbart, P. Rovero, A. Papini
P2049 Simple one-pot peptide cleavage and spontaneous macrocyclization through Paal- Knorr-like reactions using 2,5-dialkylfuran derivatives
Alex Manicardi, Atiruj Theppawong, Marleen Van Troys, Annemieke Madder
P2050 Sustainable Scale-Up of GLP-1 Agonist Peptides through Green Solid Phase Peptide Synthesis
L. Pacini, M. Muthyala, R. Zitterbart, P. Rovero, A. Papini
P2051 Searching for peptide inhibitors of TNFR2/TNFαcomplex formation using a virtual
Paulina Stencel, Artur Giełdoń, Beata Gromadzka, Sylwia Rodziewicz-Motowidło, Marta Spodzieja
P2054 Core-shell type resins for SPPS
Kwanwoo Kim, Seok-In Kim, Yoon-Sik Lee
P2055 Nature-inspired unique antimicrobial peptides from Chilean marine sediments
L. I. Beyer, A.-B. Schäfer, A. Undabarrena, I. Mattsby-Baltzer, D. Tietze, E. Svensson, A. Stubelius, M. Wenzel, B. Camara, A. A. Tietze
P2056 The role of the quorum sensing peptide PlnA in the microbiome-sarcopenia axis
Amélie Descamps, Anton De Spiegeleer, Liesbeth Crombez, Morten Kjos, Evelien Wynendaele
P2058 Unlocking Mango's Peptide Potential: Exploring Bioactive Peptides in Pulp, Peel and Seed
Mahya Bahmani, Michelle L. Colgrave, Cassandra L. Pegg, Angéla Juhász
P2059 Alca1, a cyclotide extracted and isolated from Allexis cauliflora (Violaceae): Synthesis and biological activities
Olivier Ndogo Eteme, Letícia Oliveira Catarin Nunes, Marcela Nunes Argentin, Norival Alves Santos-Filho, Ilana Lopes Baratella Da Cunha Camargo, Eduardo Festozo Vicente
P2060 Microporous Scaffold-Mediated Myeloid Cell Activation in Situ for Robust Peptide-Based Cancer Vaccine
Shao-Hua Zhuo, Wen-Hao Li, Jing-Yun Su, Yan-Mei Li
P2062 The “Sand in a gearbox” effect of antimicrobial peptides: beyond pore formation on model membranes and real bacteria cells
Daniela Roversi, Z. Vaezi, A. Bortolotti, C. Di Stefano, S. Bonacorsi, V. Santucci, C. Aisenbrey, M. M. Konai, Y. Acharya, R. Khosravi-Far, B. Bechinger, J. Haldar, L. Stella
P2064 Design and Structural Analysis of Fluorinated Polyproline-Type Foldamers and their Ability to Interact with Membrane Models
Chloe Cayrou, Simon Gonzalez, Astrid Walrant, Delphine Ravault, Karine Guitot, Sylvie Noinville, Françoise Illien, Sandrine Sagan, Thierry Brigaud, Olivier Lequin, Sandrine Ongeri, Gregory Chaume
P2065 Cyclic peptides as Connexin43 and Pannexin1 inhibitors for the treatment of inflammatory disorders
Debora Iaculli, Arthur Lamouroux, Malaury Tournier, Jade Montgomery, Anne Caufriez, Mathieu Vinken, Filippo Molica, Brenda R. Kwak, Steven Ballet
P2066 Antimicrobial peptidomimetics: design, synthesis, and surface binding
Marc Mathieu
P2067 New Insights Into Antibacterial And Antitumor Effects Of Structurally Versatile Amino Acid- Based And Non-Proteinogenic Compounds
Martina I. Peeva, Maya G. Georgieva, Aneliya A. Balacheva, Svetoslav Dimov, Nikolay T. Tzvetkov
P2068 Chemical Synthesis and Intracellular Delivery of P53 Transactivation Domain (TAD) Constructs
Mo’ath Yousef, Vladimir Torbeev
P2071 Development of a retro-inverso tetrapeptide collagen modulator as anti-aging active principle
Fosca Errante, Marco Pallecchi, Gianluca Bartolucci, Elena Frediani, Francesca Margheri, Lisa Giovannelli, Anna Maria Papini, Paolo Rovero
P2076 A BMP-2-derived peptide conjugated to chitosan improves osteoblast proliferation and antibacterial properties of membranes for oral surgery
Cristian Balducci, Annj Zamuner, Martina Todesco, Andrea Bagno, Antonella Pasquato, Giovanna lucci, Federica Bertela, Chiara Battocchio, Luca Tortora, Luca Sacchetto, Paola Brun, Erilberto Bressan, Monica Dettin
P2077 Transmembrane peptide-loaded ionic liquid nanocarriers targeting ErbB2-positive cancer
Helal Abujubara, Pankaj Bharmoria, Samantha W. Alvarez, Enoch Appiah, Kasper Moth- Poulsen, Volkan I. Sayin, Alesia A. Tietze
P2078 Characterization of Aurora-A Activation and Allosteric Regulation by TACC-3 Peptidomimetics
Diana Gimenez, Martin Walko, Jennifer A. Miles, Richard Bayliss, Megan H. Wright, Andrew J. Wilson
P2080 Synthesis, conformational analysis and biological activity evaluation of novel antiviral peptides blocking the SARS-CoV-2 cell-entry
M. Quagliata, M.A. Stincarelli, A. Di Santo, L. Pacini, F. Real-Fernandez, R. Arvia, S. Rinaldi, S. Giannecchini, A.M. Papini, P. Rovero
P2083 Synthesis, characterization and biological activity evaluation of a dual-drug based on the antibacterial peptide lugdunin functionalized with the Carbonic Anhydrase sulfonamide inhibitor acetazolamide
M. Quagliata, F. Brenzini Biagioni, S. Giovannuzzi, V. De Luca, C. Capasso, A. Nocentini, C. T. Supuran, P. Rovero, A.M Papini
P2085 Phosphorylation and GlcNAcylation of the RNA polymerase II C-Terminal domain and their effect on recognition by Pin1 and Protein Phosphatase 1
Alina Herfort, Emanuele Piemontese, Corina Maller, Maja Köhn, Oliver Seitz
P2086 How a single non-conventional amino acid can modify the effectiveness of amphibian antimicrobial peptides
Maria Rosa Loffredo, Bruno Casciaro, Giacomo Cappella, Rosa Bellavita, Diego Brancaccio, Floriana Cappiello, Francesco Merlino, Paolo Grieco, Lorenzo Stella, Alfonso Carotenuto, Maria Luisa Mangoni
P2087 Development of bioactive peptides of cosmetic interest through environmentally sustainable processes
L. Sforzi, F. Errante, J. Makowska, P. Rovero, A. Papini
P2088 Thermodynamic and kinetic effects on the activity and selectivity of antimicrobial peptides
F. Carneri, E. Franci, C. Troiano, G. Giaquinto, A. Leoci, D. Roversi, M. R. Loffredo, Y. Park, A. Toto, S. Gianni, M. L. Mangoni, H. Franzyk, L. Stella
P2091 Different approaches in optimisation of miniprotein structure for improvement of affinity towards target and inhibitory activity
Paweł Noceń, Łukasz Berlicki
P2092 Developing autoinducing peptides for regulating the quorum sensing system in S. lugdunensis
Iben Jensen, Benjamin S. Bejder, Martin S. Bojer, Hanne Ingmer, Christian A. Olsen
P2093 Design of fluorinated Aib foldamers: synthesis, structural study and capacity to interact with amyloid proteins
Marine Pietri, Olivier Monasson, Julia Kaffy, Elisa Peroni, Sandrine Ongeri, Grégory Chaume, Nathalie Lensen
P2094 Antimicrobial peptides with varied chemical compositions trigger hyperpolarization of the bacterial membrane
Anasztázia Hetényi, Kaushik Nath Bhaumik, Réka Spohn, Anett Dunai, Lejla Daruka, Csaba Pál, Tamás A. Martinek
P2095 Synthetic glucosylated peptide antigens of the bacterial protein adhesin of nontypeable Haemophilus influenzae to detect antibodies in Multiple Sclerosis
F. Nuti, F. Real-Fernandez, H. Berhane Tesfaya, P. Strauss, R. Aharoni, M. Hurevich, P. Rovero, A.M. Papini
P2098 Design, synthesis, and biological activity of tumor necrosis factor-alpha peptides for adalimumab recognition
Feliciana Real Fernandez, Andrea Di Santo, Kalina Kirilova Kirilova, Silvia Rinaldi, Gabriele Simonini, Paolo Rovero
P2099 Computational design of ultrashort peptide inhibitors for the RBD of the SARS-CoV-2 S-protein
Pengfei Pei, Shi-Zhong Luo
P2100 In vitro effect of the acidic pH on the susceptibility of the antimicrobial peptide Esc(1-21) against respiratory pathogens in cystic fibrosis lung environment
Giacomo Cappella, Maria Rosa Loffredo, Bruno Casciaro, Floriana Cappiello, Arianna Turchini, Maria Luisa Mangoni
P2103 Bismaleimidohexane-Stapled Anoplin Analogs
Magdalena Bobier, Aaron Joseph Villaraza, Portia Mahal Sabido
P2104 Glycine- and histidine-rich peptides derived from Shepherin I: study of candidacidal activity, metal-chelation properties and mode of action
Gustavo Nunes, Lohanna Lopes, Ernani Lacerda, Ana M. C. Ferreira, Carlos Marques, Breno P. Esposito, M. Terêsa Machini
P2107 ReCHEMbinant protein engineering – synthetically enhanced protein therapeutics for Myc targeting
Jan Pascal Kahler, Brecht D. Ellenbroek, Sebastian Pomplun
P2108 Cecropin A-Melittin B Hybrid CA(1-7)M(2-9) Analogs with Improved Antibacterial Activity, Low Toxicity, and Good Protease Stability
Talia Chetty, Jessica T. Mhlongo, Ayman Y. Waddad, Fernando Albericio, Beatriz G. de la Torre
P2109 Optimizing Ham Curing Process: Impact of overripening and the use of nitrifying salts on Peptide Bioactivity.
Noelia Hernández Correas, Cindy Bande-De León, Adela Abellán Guillén, Teresa Muela Clemente, Eva Salazar Serna, Jose María Cayuela García, Luis Tejada Portero
P2110 Functional and structural understanding of the angiotensin II receptor type 1 (AT1R) biased signaling
Margot Hadjadj, Alexandre Murza, Brian Holleran, Yoon Namkung, Stéphane Laporte, Richard Leduc, Mannix Auger-Messier, Pierre-Luc Boudreault
P2111 Molecular determinants of the anti-amyloid function of the cross-interaction of the human cathelicidin LL-37 with islet amyloid polypeptide
Valentina Armiento, Hendrik Wunderlich, Aphrodite Kapurniotu
P2114 Use of alternative curing salts in the cured ham production process. Effect on the generation of bioactive peptides
Cindy Bande-De León, Noelia Hernández Correas, Manuel Hernández Lorca, Pablo Gómez San Miguel, Gregorio Molina Valero, Estefanía Bueno Gavilá, María Dolores Gil Martínez, Adela Abellán Guillén
P2116 Development of a potent and specific peptide inhibitor for the E. coli MazF toxin
Luiz R. Pizzolato-Cezar, Phelipe Vitale, Carolina D. Lacerda, Mario A. R. Pineda, Roberto K. Salinas, M. Terêsa Machini
P2120 Buforin-Derived Synthetic Peptides with Potential Application in Medicine
Dana Maria Copolovici, Cristian Moisa, Andreea Ioana Lupitu, Oana Gavriliuc, Florina Bojin, Mihaela Dochia, Dorina Chambre, Lucian Copolovici
P2121 Exploring antimicrobial peptides: a new frontier in cancer treatment innovation
Lucian Copolovici, Cristian Moisa, Andreea Ioana Lupitu, Dorina Chambre, Dana Maria Copolovici
P2122 High level soluble expression of human Glucagon-Like Peptide-1 (GLP-1) analogue as a recombinant peptide in E. coli
S. Sushmita, Esha Shukla, Gaurav Pandey
P2124 Combining peptide fragments for the high-throughput generation and screening of large libraries
Anne Zarda, Xingwang Deng, Edward Will, Maylin Romero, Christian Heinis
P2126 Designed Peptide based on Plant Original Cyclic Scaffold facilitate Rheumatoid Arthritis Diagnosis
Mingshu Zhang, Sunithi Gunasekera, Liyan Mei, Erik Jakobsson, Camilla Eriksson, Helena Idborg, Per-Johan Jakobsson, Ulf Göransson
P2127 Highway to Cell: Internalization of CFTR-Stabilizing Peptides as Potent Cystic Fibrosis Treatment
Clementine Teko-Agbo, Emilie Josse, Quentin Seisel, Dean R. Madden, Magali Taulan Cadars, Prisca Boisguerin
P2128 Effects of peptide labeling on fluorescence binding assays to Src homology 2 domains: the case of protein-protein interactions inhibitors of the oncogenic phosphatase SHP2
Sara Bobone, Chiara Fulci, Chiara Innamorati, Alessia Damiani, Claudia Storti, Paolo Calligari, Daniela Roversi, Luca Pannone, Simone Martinelli, Gianfranco Bocchinfuso, Fernando Formaggio, Cristina Peggion, Barbara Biondi, Lorenzo Stella
P2129 Bicyclic peptidomimetics enable efficient transport of proteins across brain endothelium
Maria C. Lucana, Roberta Lucchi, Fabien Gosselet, Cristina Díaz-Perlas, Benjamí Oller-Salvia
P2132 Synthesis of Halogenated Cyclic RGD-Peptides as Potent SMDC-ligands
Beate Nachtigall, Norbert Sewald
P2133 Supramolecular anticoagulants with on-demand reversibility
Millicent Dockerill, Daniel J. Ford, Simona Angerani, Imala Alwis, Luke J. Dowman, Jorge Ripoll-Rozada, Rhyll E. Smythe, Joanna S. T. Liu, Pedro José Barbosa Pereira, Shaun P. Jacksond, Richard J. Payneb, Nicolas Winssinger
P2134 Adalimumab and anti-adalimumab antibodies a novel method of detection and quantification in human sera based on surface plasmon resonance technique
Andrea Di Santo, Fosca Errante, Manuela Capone, Alessandra Vultaggio, Matteo Accinno, Lorenzo Cosmi, Francesco Annunziato, Anna Maria Papini, Paolo Rovero, Feliciana Real-Fernandez
P2136 Innovative liquid chromatographic-mass spectometric technologies to purify and identify biologically active antibody-drug conjugates
Margherita Marino, Paolo Rovero, Walter Mier, Hendrik Rusche, Anna Maria Papini
P2140 High-Throughput Permeability Assay for the Discovery of Cell Penetrating Cyclic Peptides
Hanna Stokes, Noora Azadvari, Parisa Hosseinzadeh
P2143 UL144-derived peptides as modulators of the BTLA/HVEM signaling pathway
Magdalena Lipińska, Piotr Ciura, Sylwia Rodziewicz-Motowidło, Anna Wardowska, Marta Spodzieja
P2144 β-Hairpin peptide fibrillation and bacteria trapping in hydrogel
Peiyan Yu, Mrunmayee Deshpande, Nhan Dai Thien Tram, Pui Lai Rachel Ee
P2145 Peptide Nanonets as Antimicrobial and Anti-inflammatory Agents
Pui Lai Rachel Ee, Nhan Dai Thien Tram, Jian Xu, Dhanya Mahalakshmi Murali, Peiyan Yu, Wai Shiu Fred Wong, Lakshminarayanan Rajamani
P2146 Protein-Protein Interactions: Unraveling the link between HTLV-1 Tax-1 oncoprotein and human Drosophila discs large tumor suppressor
Wael El Yazidi Mouloud, Sibusiso B. Maseko, Yasmine Brammerloo, Inge Van Molle, Adria Sogues Castrejon, Charlotte Martin, Remaut Han, Steven Ballet, Oleksandr Volkov, Jean-Claude Twizere
P2148 Esc peptides for novel therapeutics against Pseudomonas aeruginosa pulmonary infections: beyond antimicrobial activity
Maria Rosa Loffredo, Loretta Ferrera, Floriana Cappiello, Bruno Casciaro, Giacomo Cappella, Ivana D’Angelo, Y. Peter Di, Maria Luisa Mangoni
P2150 Synthesis and antimicrobial activity of hybrid peptides as dual inhibitor of intracellular targets in ESKAPE pathogens
Aman Kumar Mahto, Rikeshwer Prasad Dewangan
P2152 Disrupting the RANK-TRAF6 Interface: A Novel Approach for Bone Metastases Treatment
Sofia A. Martins, Cátia Rosa, Marco Cavaco, Rita Melo, David Andreu, Javier Valle, Vera Neves, Miguel A. R. B. Castanho, João D.G. Correia
P2154 Targeting MRGPRX2 with venom peptide P17: A therapeutic avenue for DSS-Induced colitis
Karthi Duraisamy, Mukesh Kumar, Abdullah Nawabjan, Emily Kwun Kwan Lo, Benjamin Lefranc, Elsa Bonnafé, Michel Treilhou, Hani El-Nezami, Billy K.C. Chow, Jérôme Leprince
P2158 Fight-TB: Design of Novel Vaccine Antigens to Fight Tuberculosis
Marina Sala, Giovanni Barra, Maria Carmina Scala, Pietro Campiglia, Rita Berisio, Alessia Ruggiero
P2161 Advances on the green synthesis of Etelcalcetide
Koula Achilleos, Andreas Sergides, Styliana Mirallai, Charalambos Ioannou, Vicky Nicolaidou, Christos Petrou, Christakis Sergides, Yiannis Sarigiannis
P2163 Determination of the Oligomerization States of the Transmembrane Domains from SARS-CoV-2 Membrane Proteins
Tyler G. Hobart, Andrew M. Rehak, Timothy M. Reichart
P2164 Exploiting the features of short peptides to recognize specific cell surface markers
Michela Buonocore, Angelo Santoro, Enza Napolitano, Elena Ciaglia, Francesco Montella, Francesca Boccafoschi, Valeria Perugini, Matteo Santin, Anna Maria D’Ursi
P2167 Obtaining, Optimizing, and Evaluating the Activity of Anticancer LfcinB-Derived Peptides on in vitro Models against Melanoma
Karla Rodriguez, Jose Mendoza, Javier García, Zuly Rivera, Joel Lopez, Ricardo Fierro
P2169 Design and characterization of a multistage peptide-based vaccine platform to target Mycobacterium tuberculosis infection
Chiara Bellini, Emil Vergara, Fruzsina Bencs, Szilvia Bősze, Denis Krivić, Bernadett Bacsa, Sára Eszter Surguta, József Tóvári, Rajko Reljic, Kata Horvati
P2171 Engineering mRNA display for GPCR drug discovery – de novo discovery of cyclic peptide GLP1R binders
Esther Meron, Jens C. Nielsen, Mads M. Nygaard, Dennis Worm, Ulrike Leurs, Morten Lundh, Joseph M. Rogers
P2172 Novel functionalized acylation reagents for Glyand Lys-His tag acylation on proteins
Delphine N. Møller, Christian Kofoed, Mikkel B. Thygesen, Kasper K. Sørensen, Tuule Treiberg, Knud J. Jensen
P2173 KLVFF peptide functionalization of graphene oxide as suitable Aβ biomarker detection platform
Rita Turnaturi, Giuseppina Sabatino, Giuseppe Di Natale, Giuseppe Nocito, Angela Scala, Viviana Scuderi, Simona Filice, Antonino Mazzaglia, Silvia Scalese, Giuseppe Pappalardo
P2174 On-Resin Synthesis and Modification of Novel Peptide Heterocycles
Ciaran McGrory, Eddie Myers
P2175 Use of Green Solid Phase Peptide Synthesis to Obtain Tripeptide-85
M. C. O. A. Brasil, C. R. Princival, V. Kuchenbecker, E. Katekawa, W.V. Magalhães, E.M. Cilli
P2176 Affinity Peptide Extraction Using Small-Molecule, Thermoresponsive Zwitterionic Liquid Materials
Yen-Ho Chu, Yu-Hsin Chung
P2178 Optimization of pDNA delivery by WRAP cell-penetrating-peptide
K. Konate, S. Deshayes, P. Boisguérin, E. Vivès, S. Faure, P. De Santa Barbara
P2180 Application of coumarin-type chemiluminophore toward in vivo detection
Yukie Nohara, Keiko Taniguchi, Hiromi Ii, Shun Masuda, Hiroko Kawakami, Masakatsu Matsumoto, Susumu Nakata, Toshiyuki Sakai, Taku Yoshiya
P2181 Development of novel automated solid phase peptide synthesizers ensuring economic, effective, scalable and green synthesis
Krisztina Kiss, Soma Ránky, László Molnár
P2183 Discovery and Characterization of a Short Peptide Possessing a Latent Warhead Undergoing Intramolecular Cyclization in the Aqueous Environment
Riku Katsuki, Masumi Taki
P2186 A fishing technology of glycated peptides
F. Nuti, M. Marino, P. Ledwon, R. Latajka, A. Lapolla, M. Chorev, P. Rovero, A.M. Papini
P2188 Programmable Chemical Synthesis & in-situ Modifications of Peptides
Jacopo Zero, Tristan Tyler, Leroy Cronin
P2191 Peptide-based Coacervates as Evolutionary Roads of Catalytic Function
David Reis, Sara Pereira, Ana P. Ramos, Pedro M. Pereira, Leonor Morgado, Ana S. Pina
P2194 An all-in-one automated peptide purification and synthesis solution
Luísa Aguiar, M. Muthyala, S. Lüdtke, Dominik Sarma, Robert Zitterbart
P2195 Riding new Tides: Synthesis of oligonucleotides on PurePep® Chorus
Luisa Aguiar, Dominik Sarma, Robert Zitterbart
P2196 The first endocrine-disrupting chemical inhibiting a coactivator peptide’s binding
Masaki Iwamoto, Takahiro Masuya, Mari Hosose, Tomaka Ishibashi, Ayami Matsushima
P2197 PYY peptides and Fc-PYY conjugates selectively agonise Y2R
Elise Bernard, Siobhan O’Brien, Nicole Burmeister, Jacqueline Naylor, Stephanie Oldham, Arthur Suckow, Hamid Salari, Maria A. Bednarek
P2200 Pipeline for development of acylated peptide-based CGRP receptor antagonist with extended half-life for migraine treatment
Jens Bjelke Kristensen, Lisbeth Elster, Morten Lundh, Borja Ballarín-González, Flora Alexopoulou, Martin Kræmer, Ditte Marie Jensen, Ulrike Leurs, Jens Christian Nielsen, Henrik H. Hansen, Matilda Degn, Kristian A. Haanes
P2201 Peptide-conjugates derived from bacterial ParE toxin: synthesis and biological studies
Jose Gregorio Martín Bedoya, Naiara Maia Pereira, Reinaldo Marchetto
P2202 Identification and Characterization of Small Molecule Nucleotide Binding and Oligomerization Domain 2 (NOD2) Receptor Agonists
Liora E. Wittle, Karl L. Ocius, Marcos M. Pires
P2203 Influence of Hydrophobic Moieties on the Formation and Stability of Collagen Heterotrimers
Maša Stopinšek, Valdrin Islami, Giuseppe Antoniazzi, Philipp Bittner, Renato Zenobi, Helma Wennemers
P2207 Exploring Novel Peptide-Based Natural Products as a Payload for the Generation of Antibody and Peptide-Assisted Targeted Cancer Therapy
Suzie M. Chan, Makhdoom Sarwar, Jeanine Giarolla Vargas, J. da Silva, Margaret A. Brimble, Iman Kavianinia
P2208 Bispecific DNA-Peptide Conjugates for Targeting Cancer Cells
Pritam Ghosh, Huyen Dinh, Oliver Seitz
P2209 Memantine and Adamantine KLVFF Conjugates: Synthesis, Ab interaction and Effects on Recognition Memory in Mice.
Giuseppe Pappalardo, Eleonora Bocchieri, Stefania Zimbone, Maria Laura Giuffrida, Giuseppe Di Natale, Giuseppina Sabatino, Graziella Vecchio, Santina Chiechio
P2210 Chemoselective arylation of amino acids, peptides and proteins
Ahmed M. Embaby, Sanne Schoffelen, Christian Kofoed, Morten Meldal, Frederik Diness
P2211 Glycopeptides as synthetic antigenic probes for MOG Antibody-Associated Disease
Silvia Braccia, Feliciana Real-Fernandez, Christine Patte-Mensah, Christian Klein, Nicolas Collongues, Jérôme de Sèzed, Paolo Rovero, Anna Maria Papini
P2212 Designing self-assembling lipopeptide for tissue regeneration
Dhriti Shenoy, Lauren Roberts, Michela Pesenti, Kaliroi Peqini, Stefania Crespi, Cécile Echalier, Gilles Subra, Sara Pellegrino
P2213 Optimizing biological activity of Lactoferricin derived peptides: Conjugation with non peptidic motifs as a strategy
Daniel Castellar, Javier García, Zuly Rivera, Ricardo Fierro
P2215 Introducing Novel Titanium Binding Peptides; Effect of the Sequence of Amino Acids on Their Adsorption Energy to TiO2
Roja Rahmani, Alexander P. Lyubartsev
P2216 Peptides Conjugated to Sugars as Therapeutics for Ebola & Cancer disease
Fayna García-Martín, Óscar Suárez, Gonzalo Millán, Filipa Marcelo, Ana Gimeno, Elena Lalinde, Jesús R. Berenguer, Juan Anguita, Héctor Busto, Jesús Manuel Peregrina, Asuka Nanbo, Jesús Jiménez-Barbero, Francisco Corzana
P2217 Synthetic strategies to prepare novel bioactive lysine and peptide conjugates with triazolium derivatives
Claudia Bello, Michał Jewginski, Patrycja Ledwon, Francesca Nuti, Paolo Rovero, Rafal Latajka, Anna Maria Papini
P2222 Effect Of Azaglycine On The Internalization Of Penetratin Derivatives
Karima Tarchoun, Dóra Soltész, Ildikó Szabó, Zoltán Bánóczi
P2223 Molecular Design for Cytosolic Delivery of Antibodies Using an Intracellular Delivery Peptide
Yoshimasa Kawaguchi, Shiroh Futaki
P2224 Synthesis and characterization of nucleolin receptor recognizing F3 peptide fragment-drug conjugates
Bettina Basa, Diána Vári-Mező, Kata Nóra Enyedi, József Tóvári, Szilvia Bősze, Krisztina Kiss, Gábor Mező
P2225 Leuprorelin Peptide Drug Complexes with Permeability Enhancers to Increase Bioavailability
Adel Penhasi, Zeina Zaatari, Moustafa Ghanyem, Deborah E. Shalev
P2226 Designing selective peptide binders for Methicillin resistance Staphylococcus aureus
Yaara Zandany, Zvi Hayouka
P2228 Phosphopeptides as a replacement of bisphosphonates for bone targeting
Mazen Jamous, Barbara Roether, Uwe Haberkorn, Walter Mier
P2231 Site-specific Conjugation of Cell-penetrating Peptides: A Strategy to Ameliorate Antibody Therapy
Niklas van den Bergh, Verena Merke, Sabrina Wohlfart, Philipp Uhl, Walter Mier
P2234 Synthesis of cell-penetrating peptides with peroxisomal targeting signal 1
Christine Krofta, Anne Sophie Hammann, Sven Thoms, Norbert Sewald
P2235 Surface peptide-modified black phosphorus nanosheets: a novel multifunctional nanoadjuvant
Tian-Yang Wang, Wen-Hao Li, Xue-Feng Yu, Yan-Mei Li
P2236 Non-ionic surfactants for the solubilisation of lipopeptides and enhancement of their biological activity
Ágnes Ábrahám, Gergő Gyulai, Judith Mihály, Andrea Horváth, Orsolya Dobay, Éva Kiss, Kata Horváti
P2238 Nanobody CDR3 loop peptidomimetic improves binding on living Acinetobacter baumannii
Kevin Van holsbeeck, Anke Breine, Charlotte Martin, Morgane Mannes, Els Pardon, Jan Steyaert, Han Remaut, Charles Van der Henst, Steven Ballet
P2239 High-Throughput Analysis of Peptide Accumulation in Mammalian Cells
Sobika Bhandari, George Ongwae, Marcos M. Pires
P2240 Electrostatically modulated peptide-based drug delivery against resistant cancer
Yvonne Christian, Amay Sanjay Redkar, Naveen Kumar, Shine Varghese Jancy, Aneesh Chandrasekharan, T.R. Santhoshkumar, Vibin Ramakrishnan
P2241 Novel viral peptide-based tandemized carriers: Structure prediction and in vitro evaluation
Katalin Uray, Martin Krátký, Jiří Horčic, Levente Lakatos, Előd Méhes, Bálint Jezsó, Jarmila Vinšová, Szilvia Bősze
P2242 Small Additive Molecules to Enhance the Effective Accessibility of Delivered Nucleic Acid by Cell-Penetrating Peptide
Geeta Arya, Ly Porosk, Chigozie Nkwocha, Margus Pooga
P2244 Fluorogenic cell surface labelling using fluorescent molecular rotor-labelled peptide boronic acid conjugates
Alen Koçak, Pritam Ghosh, Oliver Seitz
P2247 Synthesis and application of β-amino γ-lactam (Bgl) residues
Charity D. Yongo-Luwawa, William D. Lubell
P2250 Development of Cyclopropane-Based Foldamers Mimicking Protein Secondary Structures
Makoto Nagata, Nanase Ochiai, Akiko Yoshida, Satoshi Shuto, Mizuki Watanabe
P2253 Gq protein peptidomimetics as allosteric modulators of the ghrelin receptor
Morgane Mannes, Esaü Vangeloven, Charlotte Martin, Marjorie Damian, Sonia Cantel, Jean-Alain Fehrentz, Julie Kniazeff, Jean-Louis Banères, Steven Ballet
P2255 A reductive amination approach for the synthesis of catalytic peptide foldamers
M. Pollastrini, A. Moretto
P2257 DARPin-based Pretargeting: Zeroing in on Cancer
K. Westerlund, M. Oroujeni, A. Van Deventer, Z. Wang, J. Clinton, I. Zelepukin, E. Papalanis, Y. Liu, A. Orlova, V. Tolmachev, A. Eriksson Karlström
P2258 Rational design of novel peptidomimetics against influenza a virus: biological and computational studies
M.C. Scala, M. Agamennone, M. Marchetti, F. Superti, P. Campiglia, M. Sala
P2259 Development of peptide nucleic acids-based molecules targeting non-canonical nucleic acids structures
Matilde Rossia, Paola Gratteri, Anna Maria Papini, Carla Bazzicalupi
P2260 Macrocyclic mimetics of the Suppressor of Cytokine Signaling 1 and 3 proteins (SOCS1-SOCS3)
A. Cugudda, S. La Manna, D. Florio, D. Marasco
P2262 Modulation of the antagonistic properties of an insulin mimetic peptide by disulfide bridge modifications
Marta Lubos, Jan Pícha, Irena Selicharová, Jíří Žák, Miloš Buděšínský, Katarína Mitrová, Lenka Žáková, Jiří Jiráček
P2263 Combinatorial libraries of bipodal insulin receptor binders
Irena Selicharová, Benjamin Fabre, María Soledad Garre Hernández, Marta Lubos, Jan Pícha, Zdeněk Voburka, Katarína Mitrová, Jiří Jiráček
P2266 AI-driven design of β-secretase 1 inhibitors
Marko Njirjak, Daniela Kalafatovic, Goran Mauša
P2267 Application of Deep learning Imputation to Peptide Bioactivity and Property Prediction
Samar Mahmoud, Himani Tandon, Matthew Segall, Ruibo Zhang, Robert E Thompson, Jeffrey W Schubert, Dipannita Kalyani, Dan Sindhikara
P2268 PICKAPEP: Visualization and Calculation of Cyclized and Modified Peptidomimetics Made Easy
Vanessa Erckes, Mattis Hilleke, Clemens Isert, Christian Steuer
P2274 Metalloproteins Investigation for the Development of new Inhibitors
Matteo Orlandi, Piero Procacci, Marina Macchiagodena, Fabrizio Carta, Claudiu T. Supuran, Marco Pagliai
P2275 Deep learning for Peptide Classification: From Data to Effective Models
Marko Njirjak, Marko Babić, Patrizia Jankovic, Erik Otović, Daniela Kalafatovic, Goran Mauša
P2276 Scoring the Synthesizability of Any Novel Non-natural Amino Acid
Gökçe Geylan, Mikhail Kabeshov, Samuel Genheden, Thierry Kogej, Ola Engkvist, Leonardo De Maria
P2277 Chemoenzymatic synthesis of protein pseudo-[2]rotaxane
Elodie Soehnlen, Shalene Ofner, Judit Osz, Natacha Rochel, Vladimir Torbeev
P2279 Structural and Mechanistic Insights Into the Advances of FXIIIa Inhibitors
Ivan P. Bogdanov, Arijit Biswas, Diana Imhof, Nikolay T. Tzvetkov
P2280 Can large scale structural modeling be applied to peptide screening and deorphanization?
Shaima Hashem, Jérôme Leprince, Pierre Tuffery
P2281 Impact of backbone N-amination on the stability of parallel beta-sheets
Syrah Starnes, Seth Horne, Juan Del Valle
P2283 How do Disulfide, Thioacetal and Lanthionine Bridges Influence the Conformations of Macrocyclic Peptides?
William T. P. Darling, Lianne H. E. Wieske, Declan T. Cook, Abil E. Aliev, Laurent Caron, Emily J. Humphrys, Angelo Miguel Figueiredo, D. Flemming Hansen, Máté Erdélyi, Alethea B. Tabor
P2284 Characterizing bradykinin-derived membrane-sensing peptides through Molecular Dynamics
Carlo Guardiani, A. Giacomello
P2285 Effect of antifreeze activity and lipid interaction of tryptophan scanning of 11-residue lysine homopeptide
R. Rojas, M. Aróstica, C. Cardenas, L. Aguilar, F. Albericio, F. Guzmán
P2286 Structural Ensemble of Peptide-induced Membrane Poration by Heterogeneous Magainin Peptides
Bing Zan, Charles Chen, Martin Ulmschneider, Jakob Ulmschneider-Mayer
P2288 Helical peptides bearing dual triplet-spin/fluorescent labels enable the first parallel distance measurements by electron spin resonance and Förster resonance energy transfer
Marta De Zotti, Arnau Bertran, Chiara Dalla Torre, Jack Sawyer, Derren Heyes, Sam Hay, Christiane Timmel, Marilena DI Valentin, Alice Bowen
P2289 Antiparallel β‐Double Helices from α,γ-Hybrid Peptides
DRGKoppalu R. Puneeth Kumar, Gijo George, Uddipan Bhattacharya, Arnab Mukherjee, Hosahudya N. Gopi
P2290 Aromatic-aromatic interactions as an intrinsic modulator of amyloid formation
Artem Pavlov, Beate Koksch
P2291 Structure-Activity Relationship Study of β-Hairpin Peptides with Antibiotic Activity
Aparna Palakkurussi Rathessan, Suvrat Chowdhary, Johannes Kupke, Marcus Fulde, Beate Koksch
P2293 Molecular insights into the lipid bilayer interaction of the cyclic lipodepsipeptide tolaasin
Benjámin Kovács, Tünde Juhász, Niels Geudens, José C. Martins, Tamás Beke-Somfai
P2294 A comprehensive structural study on AT1 Receptor Variants: Towards the Design of Potent Biased Agonists
Malihe Hassanzadeh, Audrey Collette, Brian Holleran, Stéphane Laporte, Richard Leduc, Pierre-Luc Boudreault
P2295 Structural analysis of a peptide-based simplified model reproducing SARS-CoV-2 S RBD/ACE2 binding site
Michela Buonocore, Rosanna Lucignano, Angelo Santoro, Anna Maria D’Ursi, Delia Picone
P2296 Planar aggregation of the influenza viral fusion peptide alters membrane structure and promotes poration
Richard W. Pastor, Amy Rice, Paul S. Blank, Joshua Zimmerberg
P2298 Unlocking HIV's Secrets: Synthesis of Histone H3K36Me3 to Investigate LEDGF Protein Binding to Modified Nucleosomes using Cryo‐Electron Microscopy
Ramesh M. Chingle, Samanthreddy Kedika, Tao Jing, Dmitry Lyumkis, Terrence R. Burke
P2300 Elucidating the role of phosphoserines in Tau protein by combined computational and synthetic methods
Martina Tuberti, Fintan Kelleher, Gemma K. Kinsella
P2300 Elucidating the role of phosphoserines in Tau protein by combined computational and synthetic methods
Martina Tuberti, Fintan Kelleher, Gemma K. Kinsella
P2301 Theoretical and biological studies of oxytocin containing conformationally fixed analogue of Tyrosine Tic(OH) (1,2,3,4-Tetrahydro-7-hydroxyisoquinoline-3-carboxylic acid)
Michal Lebl, Jiří Jiráček, Marta Lubos, Jakub Kaminský
P2305 Can we improve Coarse-Grained simulations of peptide selfassembly and aggregation by cluster analysis inputs?
Marko Babić, Daniela Kalafatović
P2306 Design and Exploration of Tubular Assemblies of Hybrid Cyclic Peptides
Souvik Panda Mahapatra, Hosahudya N. Gopi
P2307 Antimicrobial and cell-adhesive peptide-based hydrogels for biomedical applications
Nabila Mehwish, Patricia López-Gómez, Maria Pau-Ginebra, Carles Mas-Moruno
P2309 De novo design of collagen-like peptides for cell-based technologies
Maryana Baran, Eileen Gentleman, Maxim Ryadnov
P2310 Self-assembling dipeptides as vehicles for the delivery of peptide therapeutics
Peter Divanach, Eirini Fanouraki, Vagelis Harmandaris, Anastassia N. Rissanou, Anna Mitraki
P2314 Self-assembly of histidine-containing peptides and applications
C.P Apostolidou, Chrysoula Kokotidou, Varvara Platania, Vasilis Nikolaou, Georgios Landrou, Emmanouil Nikoloudakis, Georgios Charalambidis, Maria Chatzinikolaidou, Athanassios G. Coutsolelos, A. Mitraki
P2315 Tuning the Assembly of Proteins and Peptides in Lipid Bilayers
Sebastián Jiménez Millán, Ivan Sasselli, Armando Maestro
P2318 Design of fluorinated peptide-based hydrogels for sustained drug release application
Aurélie Honfroy, Jolien Bertouille, Ana-Maria Turea, Thibault Cauwenbergh, Jessica Bridoux, Nathalie Lensen, Jessica Mangialetto, Niko Van den Brande, Jacinta F. White, James Gardiner, Thierry Brigaud, Steven Ballet, Sophie Hernot, Grégory Chaume, Ch
P2319 Single glycans shape viscoelastic properties of a mucin-inspired peptide hydrogel
Jonas Proksch, Marlene Dal Colle, Frederick Heinz, Jacqueline Gottwald, Robert Schmidt, Martina Delbianco, Bettina Keller, Ulrike Alexiev, Michael Gradzielski, Beate Koksch
P2330 Cardiolipin-specific peptides, designed to possess cell penetrating ability, rescue mitochondrial dysfunction
Gwangsu Shin, Dongwoo Kim, Yoonhwa Choi, Hyeong woon Choe, Seung Hee Yang, Jaehoon Yu
P2331 Efficient synthesis of three-helix bundle proteins using ligase-mediated trimerization of HIV-1 fusion inhibitor T20 on a dendrimer scaffold
Xiaohong Zhang, Yiyin Xia, Chuan-Fa Liu, James P. Tam
P3332 Broaden the Applications of Peptidyl Asparaginyl Ligases
Yiyin Xia, Hongxia Li, Jiayong Liu, James P.Tam, Chuan Fa Liu